Sensors, MEMS, Electronics – Page 113

Diamond-based Biosensors with an Impedimetric and Label-free Read-out

Vermeeren V., Bijnens N., Grieten L., Wenmackers S., Vanden Bon N., Haenen K., Wagner P., Michiels L., Hasselt University, BE

Healthcare and diagnostics are moving towards molecular medicine. Hence, a lot of research is being performed on biosensors. However, rarely one has reached the commercialization phase because of the expensive infrastructure required for signal read-out. [...]

Nanoparticle-coated nanosprings for diagnostic applications using SERS based detection

Sai V.V.R., University of Idaho, US

Significant enhancements in the SERS signals may be obtained with elongated arrangement of silver or gold nanoparticles. Silica nanosprings (NS) with high surface to volume ratio are promising candidate to yield such sensor materials. In [...]

Nanopore/electrode structures for single molecule biosensing

Albrecht T., Imperial College London, UK

In this contibution I will present some of our work on solid-state nanopores, the fabrication of nanopore/electrode structures and how these can be used for single-molecule biosensing applications (DNA, proteins etc.). Specifically, I will introduce [...]

Label-Free, Electrical Detection of the SARS Virus N-Protein with Nanowire Biosensors Utilizing Antibody Mimics as Capture Probes

Chang H.K., Ishikawa F., Chiang P.C., Zhou C., University of Southern California, US

In this report, we introduce evolved AMPs as a new class of capture agents for nanowire/nanotube biosensors, and demonstrate selective detection of a protein related to severe acute respiratory syndrome (SARS), using devices based on [...]

Towards an asynchronous magnetic bead rotation method for immunological assays

Hecht A., Kinnunen P., McNaughton B., Kopelman R., University of Michigan, US

Much attention has been focused on using magnetic particles for biodetection applications on chip. Most of these applications involve using the magnetic particles either for translational motion in a magnetic field, or as labels for [...]

SiCN nanomechanical resonators for array-based biosensor applications

Guthy C., Singh A., Tanha J., Evoy S., University of Alberta, CA

Rapid, sensitive and inexpensive analysis of biological molecules is of great importance to many biomedical applications, such as disease detection and monitoring, drug discovery, detection of pathogens, etc. Mechanical resonators have been demonstrated as highly [...]

Label-free, Fluorescenece Detection of DNA Nanoparticle Scaffolds

Kell A.J., Tan S., Charlebois I., Boissinot M., Simard B., National Research Council, CA

We have developed a nanoparticle-based DNA biosensor that can detect unlabelled ssDNA with good sensitivity (picomolar concentrations). The biosensor makes use of the optical changes of a cationic polymer interacting with ssDNA versus that of [...]

Bio Sensors, Diagnostics & Imaging

Guidelines for Verilog-A Compact Model Coding

Depeyrot G., Poullet F., Dolphin Integration, FR

Verilog-A has practically become the standard for developing and coding compact device models. However, contrarily to the Verilog standard, where the IEEE has defined syntax and semantic rules for both simulation and synthesis (IEEE1364-2001 and [...]

Modeling of Mismatch and Across-Chip Variations in Compact Device Models

Lu N., IBM, US

For analog circuit designers, both reducing device mismatch and having a good device mismatch model are very important. Pelgrom characterized device mismatch between two devices separated by a finite distance D as sqrt[a^2/(W*L) + b^2*D^2]. [...]