FR – TechConnect Briefs

An innovative device to determine the partial pressure of volatile components via substrate-integrated hollow waveguide infrared spectroscopy with integrated microfluidics

Bernard, G., Gabriel, J.-C.P., Kokoric, V., Mizaikoff, B., Penisson, C., Theisen, J., Wilk, A., Zemb, T., CEA, FR

A microfluidic system combined with substrate-integrated hollow waveguide (iHWG) vapor phase infrared spectroscopy has been developed for evaluating the chemical activity of volatile compounds dissolved in complex fluids [1]. Chemical activity is an important yet [...]

Companion diagnostic test using digital microfluidic

Boizot, F., Den Dulk, R., Fouillet, Y., Fuchs, O., Menneteau, M., Navarro, F., CEA-LETI, FR

Companion diagnostics are an indispensable part of personalized medicine, providing information that is essential for the safe and effective use of a corresponding therapeutic drug. Such devices need to be robust, transportable and easy to [...]

A stand-alone and portable microfluidic platform for quantitative multi-step assays

Boizot, F., Charles, R., Fouillet, Y., L. Achard, J-, Parent, C., Verplanck, N., CEA-LETI, FR

This paper reports an automated platform for quantitative multi-step assays composed of two main components: a microfluidic chip using collapsible chambers pneumatically actuated and a portable instrument to automate the fluidic operations. To achieve a [...]

70dB EMI shielding between 10 MHz and 10 GHZ with sprayed metallization of Ag

Stremsdoerfer, S., Jetmetal Technologies, FR

This presentation starts with the description of a new direct chemical plating method for silver, called the JET METAL (JMT) process and of the JET SELECTIVE process, which allows to obtain a selective metallization on [...]

Nanostructured Lipid Carriers to Deliver HIV p24 Antigen and CpG Immunostimulant in Mice and Non-Human Primates Immunogenicity Studies

Bayon, E., Bosquet, N., Gonon, A., Gosse, L., Le Grand, R., Marche, P.N., Morlieras, J., Navarro, F.P., CEA-LETI, FR

Fighting HIV pandemic is one of today’s major health priorities and vaccination remains the most challenging issue against HIV propagation. Until now, the best vaccine candidate showed only 30% protection in RV144 clinical trial [1]. [...]

Bedaquiline loaded lipid nanoparticles: a promising candidate for TB treatment

Ainsa, J.A., Codony, D., Coya Raboso, J.M., Freire, C., Hibbitts, A., Jary, D., Lozano-Fernandez, T., Lucia, A., Navarro, F., Pérez, D., Redinger, N., Schaible, U., Tailleux, L., CEA-LETI, FR

Increase in antibiotic resistance is a global concern worldwide[1], with 480,000 new cases of multi-drug resistant tuberculosis (MDR-TB) diagnosed each year. Therefore, the goals for the Nanotherapeutics for Antibiotic Resistant Emmerging Bacterial pathogens (NAREB) research [...]

Piezoelectric actuators, next driver for MEMS market?

Allain, M., Casset, F., Desloges, B., Dieppedale, C., Fanget, S., Le Rhun, G., Nicolas, S., CEA-LETI, FR

Over the past three decades, huge progresses have been made in MEMS technologies. Hundreds millions of MEMS, principally: accelerometers, gyroscopes and microphones, are commercialized yearly. This should continue to increase with upcoming new applications related [...]

Country: FR