FR – TechConnect Briefs

Evaporation of Gold Nanofluid Sessile Drops on Heated Substrate

Boukherroub R., Carlier J., Harmand S., Zaaroura I., Université Polytechnique Hauts-de-France (UPHF), FR

In this paper, experiments investigating the evaporation of gold nanofluid droplets to evaluate the effect of the particle size (5 and 10 nm) and concentrations (1 and 4% Cv), were executed on a hydrophobic silicon [...]

An innovative device to determine the partial pressure of volatile components via substrate-integrated hollow waveguide infrared spectroscopy with integrated microfluidics

Bernard G., Gabriel J.-C.P., Kokoric V., Mizaikoff B., Penisson C., Theisen J., Wilk A., Zemb T., CEA, FR

A microfluidic system combined with substrate-integrated hollow waveguide (iHWG) vapor phase infrared spectroscopy has been developed for evaluating the chemical activity of volatile compounds dissolved in complex fluids [1]. Chemical activity is an important yet [...]

Companion diagnostic test using digital microfluidic

Boizot F., Den Dulk R., Fouillet Y., Fuchs O., Menneteau M., Navarro F., CEA-LETI, FR

Companion diagnostics are an indispensable part of personalized medicine, providing information that is essential for the safe and effective use of a corresponding therapeutic drug. Such devices need to be robust, transportable and easy to [...]

A stand-alone and portable microfluidic platform for quantitative multi-step assays

Boizot F., Charles R., Fouillet Y., L. Achard J-, Parent C., Verplanck N., CEA-LETI, FR

This paper reports an automated platform for quantitative multi-step assays composed of two main components: a microfluidic chip using collapsible chambers pneumatically actuated and a portable instrument to automate the fluidic operations. To achieve a [...]

70dB EMI shielding between 10 MHz and 10 GHZ with sprayed metallization of Ag

Stremsdoerfer S., Jetmetal Technologies, FR

This presentation starts with the description of a new direct chemical plating method for silver, called the JET METAL (JMT) process and of the JET SELECTIVE process, which allows to obtain a selective metallization on [...]

Nanostructured Lipid Carriers to Deliver HIV p24 Antigen and CpG Immunostimulant in Mice and Non-Human Primates Immunogenicity Studies

Bayon E., Bosquet N., Gonon A., Gosse L., Le Grand R., Marche P.N., Morlieras J., Navarro F.P., CEA-LETI, FR

Fighting HIV pandemic is one of today’s major health priorities and vaccination remains the most challenging issue against HIV propagation. Until now, the best vaccine candidate showed only 30% protection in RV144 clinical trial [1]. [...]

Bedaquiline loaded lipid nanoparticles: a promising candidate for TB treatment

Ainsa J.A., Codony D., Coya Raboso J.M., Freire C., Hibbitts A., Jary D., Lozano-Fernandez T., Lucia A., Navarro F., Pérez D., Redinger N., Schaible U., Tailleux L., CEA-LETI, FR

Increase in antibiotic resistance is a global concern worldwide[1], with 480,000 new cases of multi-drug resistant tuberculosis (MDR-TB) diagnosed each year. Therefore, the goals for the Nanotherapeutics for Antibiotic Resistant Emmerging Bacterial pathogens (NAREB) research [...]

Piezoelectric actuators, next driver for MEMS market?

Allain M., Casset F., Desloges B., Dieppedale C., Fanget S., Le Rhun G., Nicolas S., CEA-LETI, FR

Over the past three decades, huge progresses have been made in MEMS technologies. Hundreds millions of MEMS, principally: accelerometers, gyroscopes and microphones, are commercialized yearly. This should continue to increase with upcoming new applications related [...]

Two-phase spontaneous capillary microflows and the transport of capillary wagons

Berthier E., Berthier J., Brakke K., Gosselin D., Lee Jing, Navarro F., Theberge A., CEA-LETI, FR

The use of capillarity to move fluids at the microscale has been soaring lately due to new applications in medicine, biology, biotechnology, energy, thermic and space. Especially of interest are open capillary channels. These channels [...]

On the use of Zisman’s function for the determination of the velocity of spontaneous capillary microflows

Berthier E., Berthier J., Gosselin D., Lee Jing, Navarro F., Theberge A., CEA-LETI, FR

Capillary-based microfluidic systems are increasingly used in the fields of biotechnology, medicine, thermics, energy and space. In such systems the energy source responsible for the flow is the surface energy of the walls. Extending the [...]