Papers:
Numerical and Analytical Studies of AC Electric Field in Dielectrophoretic Electrode Arrays
Manipulation of micro-sized particles and biological cells using dielectrophoresis (DEP) is an emerging technique in MEMS and nano technology[3]. This paper presents an exact solution of dielectrophoretic motion of a polarized particle in the vicinity [...]
Transient Analysis of Electroosmotic Flow in Nano-diameter Channels
Transient analysis of electroosmotic flow in a nano-diameter channel is presented. The time for flow to reach steady state in a nano-diameter channel for various Debye lengths is investigated by solving the Navier-Stokes equations in [...]
Direct Numerical Simulation of Moving Charged, Flexible Bodies with Thermal Fluctuations
The interaction of sub-micron scale objects with fluids is an important problem encountered in miniaturized systems. Various physical phenomena should be modeled simultaneously for a fundamental investigation of these systems. Our objective is to develop [...]
Numerical Analysis of a Microfluidic Oscillator Flowmeter Operating with Gases or Liquids
Simões E.W., Furlan R., Pereira M.T., Laboratório de Sistemas Integráveis - Escola Politécnica da Universidade de São Paulo, BR
We analyzed microfluidic oscillators operating with liquids (water, isopropilic alcohol, and acetone) or gases (nitrogen, argon, and carbon dioxide), using numerical simulation. The possible applications include rapid measurement and control of low fluid flows in [...]
Numerical Modeling of Ferrofluid Flow Instabilities in a Capillary Tube at the Vicinity of a Magnet
The use of ferrofluids is now foreseen to be important for microfluidic systems and biotechnological microsystems as microvalves, micropumps or for the control and synchronization of the flow. The advantage lies in the possibility of [...]
Novel Microfluidic Jet Deflection: Significant Modeling Challenge with Great Application Potential
A novel method is described for deflecting a liquid jet emanating from an orifice having a diameter of approximately ten microns. While awkward mechanical valves or unwieldy electrodes can be used to deflect a jet, [...]
System Performance Evaluation with SystemC for Two PCR Microelectrofluidic Systems
We present a performance comparison between two types of microfluidic systems - continuous-flow systems and droplet-based systems. The comparison based on a specific microfluidic application - a polymerase chain reaction (PCR) system. The modeling and [...]
Simulation of Hydrodynamic Dispersion in Gas/Liquid Microreactors
Dispersion and spreading of concentration signals in gas/liquid microreactors is studied with methods of computational fluid dynamics (CFD). It is shown that conventional reactor designs exhibit a broad residence-time distribution due to convective signal dispersion. [...]
A Compact Model for Flowrate and Pressure Computation in Micro-fluidic Devices
A compact model to compute flowrate and pressure in micro-fluidic devices is presented. The micro-fluidic flow can be driven by either an applied electric field or by a pressure gradient or both. In the proposed [...]
Simulation of Electrically-Excited Flows in Microchannels for Mixing Application
In the present paper we propose a method for improved mixing in microchannels. The basic idea is to excite a secondary vortex flow around an obstacle within the micromixer by applying an external oscillatory electrical [...]
Squeezing Flow of Particles and Large Molecules Suspended in a Liquid Through Nanochannels
The presentation addresses the status of current understanding of the hydrodynamic phenomena accompanied the motion of a nanometer-sized particle through a nanotube.
Electroosmotic Flow and Zone Broadening in Microfluidic Channels of Variable Cross-Section and Wall Charge
Electroosmotic flow is often the method of choice for generating fluid flows in micro fluidic devices. The resulting flow has a characteristic at profile which has the advantage of very low axial dispersion. This is [...]
Simulation of Electro-Osmotically Driven Microsythesis Systems
Modeling, optimization, and the realization of an electroosmotically driven chemical microsynthesis system for Wittig reactions are presented. Essential for good functioning of the chemical liquid reaction system is controllability of the supplied chemicals, independently of [...]
Analysis of Physico-Chemical Processes in an Amperometric Oxygen Biosensor
Krishnamoorthy S., Feng J.J., Makhijani V.B., Gao C., Choi J.W., Ahn C., CFD Research Corporation, US
Amperometric techniques are commonly used in lab-on-a-chip systems to sense various blood gas analytes such as H+, CO2, O2, etc. In the present study, a microchip-based amperometric biosensor, being developed as a part of plastic-based [...]
Modeling of Joule Heating in Electrophoretic Separation Microchips
This paper presents a model for Joule heating induced analyte dispersion in electrophoretic separation channels with a rectangular cross section. The model is in closed form and captures the effect of cross-sectional geometry. Three-dimensional numerical [...]
Separation of Long Polyelectrolytes in a Microfuluidic Channel with Constrictions: A Monte Carlo Study
We present Monte Carlo simulation results for the motion of long linear polyelectrolytes inside a microchannel of molecular dimensions, structured as a periodic array of wells linked by narrow constrictions. Molecules are driven in the [...]
Macromolecules in Microdevices: Multiscale simulation of DNA dynamics in model microfluidic geometries
Simple arguments predict that the dynamics of a dissolved macromolecule confined to a channel comparable to its equilibrium coil size (~1 um for viral DNA) are quite different from those in free solution, because of [...]
Biochemical Binding in Microspheres-Based-Imunoassays
Microspheres (referred commonly as beads) are being extensively used in biochemical assays as supports for proteins, DNA, etc. We have successfully developed computational models for simulating sample detection using flowing beads. The model fully integrates [...]
Simulation Methodology for Dielectrophoresis in Microelectronic Lab-on-a-chip
Recent trends in lab-on-a-chip show a growing use of dielectrophoresis (DEP) to manipulate biological objects such as cells and organic molecules [1], [2], [3], [4]. Bringing the advances of microelectronic miniaturization into biological and clinical [...]
Viscous Dissipation Effects For Liquid Flow In Microchannels
Different phenomena have been observed in various works indicating that the mechanisms of flow and heat transfer in microchannels are still not understood clearly. There is little experimental data and theoretical analysis in the literature [...]
End Effects of Rare Gas Flow in Short Channels and in Squeezed-Film Dampers
Simple approximate design formulas (+-5%) for calculating the elongation of the idealized viscous flow channel of rare gas at Knudsen numbers Kn < 100 due to the open end effects. Rectangular channels with a large [...]
Transient Filling Flow into Microchannels Considering Surface Tension
Kim D.S., Lee K-C, Lee S.S., Kwon T.H., Lee K-C, Lee S.S., Pohang University of Science and Technology, KR
In this paper, we investigated, both experimentally and numerically, transient “filling” flow into microchannels, which differs from completely “filled” flow in micro-channels. An experimental flow visualization system was devised to observe the characteristics of microchannel [...]
Modelling Free Jet Ejection on a System Level – An approach for microfluidics
Koltay P., Moosmann C., Litterst C., Streule W., Birkenmeier B., Zengerle R., University of Freiburg, DE
Fast simulation of complex microfluidic systems requires consideration of network simulations based on lumped models as an alternative to standard computational fluid dynamic (CDF) simulations. In this paper we describe an analytical model of an [...]
Numerical Simulation of Droplet Shapes on Rough Surfaces
It has been demonstrated that surface roughness causes superhydrophobicity. Our objective is to develop a numerical tool and study the relationship between the roughness characteristics and the apparent contact angle and motion of liquid drops [...]
Journal: TechConnect Briefs
Volume: 1, Technical Proceedings of the 2002 International Conference on Modeling and Simulation of Microsystems
Published: April 22, 2002
Industry sector: Sensors, MEMS, Electronics
Topic: Micro & Bio Fluidics, Lab-on-Chip
ISBN: 0-9708275-7-1