CFD Research Corporation – TechConnect Briefs

Nano-plamsonics Sensing and Integration with Microfluidics for a Lab-on-chip Biosensor

Wei J.J., Rexius M., Kofke M., Wang Y., Singhal S., Waldeck D.H., CFD Research Corporation, US

Ordered arrays of nanostructures in metal films have been studied for practical miniaturization of SPR sensing and microfluidic integration. We report a nanostructure array that is designed to permit significantly enhanced Extraordinary Optical Transmission (EOT) [...]

Multiscale modeling carbon nanotube growth on a supercapacitor electrode

Vasenkov A.V., CFD Research Corporation, US

Recently, the supercapacitors utilizing Carbon Nanotubes (CNTs) were reported. Currently, the fabrication of CNT-based supercapacitors involves manipulation of CNTs that is difficult and expensive owing to tiny size of CNTs. The direct deposition of well [...]

Numerical Analysis of Nanofluidic Sample Preconcentration in Hydrodynamic Flow

Wang Y., Pant K., Diffey W., Chen Z., Sundaram S., CFD Research Corporation, US

This paper presents the first, high-fidelity numerical study of nanofluidic streaming potential-based sample preconcentration. Parametric analysis is performed to capture the critical effects of pressure and background electrolyte (BGE) concentration on preconcentrator performance. Our studies [...]

Multiscale Design of a Laser Actuated Micro Bubble Array Acoustic-Fluidic Microdevice for Bioanalytical and Drug Delivery Applications

Chen Z.J., Przekwas A.J., CFD Research Corporation, US

Next generation fluidic micro-nano devices will require precise control of force fields within a device and their interaction with a biological sample. Current force field designs use mechanical structures such as cantilevers, optical fields e.g. [...]

Novel Reactor Utilizing Selective Heating Catalytic Nanoparticles for Low-Temperature Growth of Carbon Nanotubes

Vasenkov A.V., Kolobov V.V., Carnahan D., CFD Research Corporation, US

Chemical Vapor Deposition (CVD) of carbon nanotubes (CNTs) and carbon nanofibers (CNFs) is a catalytically controlled synthesis requiring catalyst temperatures in excess of 700°C. The CVD synthesis is typically accompanied by significant substrate heating which [...]

Multi-physics Simulational Analysis of a Novel PCR Micro-Device

Wang Y., Pant K., Grover J., Sundaram S., CFD Research Corporation, US

While microfluidic devices for PCR amplification have critical applications in biodefense, homeland security, forensics and diagnostics, their efficient simulation and design continue to be a challenge. An experiment-only trial-and-error approach can prove to be prohibitively [...]

Low-temperature growth of carbon nanofibers by selective heating of catalyst

Vasenkov A.V., Kolobov V.V., Melechko A.V, CFD Research Corporation, US

A critical technological challenge for many potential carbon-nanotubes (CNT) and carbon nanofibers (CNF) applications is to have a process for a direct synthesis of aligned/micropatterned CNTs/CNFs on temperature-sensitive surfaces. Currently there is no process that [...]

A Continuous Particle/Cell Sorter Using Dielectrophoresis

Wang G.R., Feng J.J., Vasantgadkar S., Pant K., Prabhakarpandian B., Krishnamoorthy S., Sundaram S., CFD Research Corporation, US

We present a novel design of a continuous microfluidic sorter for separation of cells or particles by the intelligent use of conventional negative dielectrophoresis with separation efficiency of greater than 95%. A high fidelity modeling [...]

Mixed-Methodology-Based System-Level Simulation of Biochemical Assays in Integrated Microfluidic Systems

Wang Y., Bedekar A.S., Krishnamoorthy S., Siddhaye S.S., Sundaram S., CFD Research Corporation, US

While lab-on-a-chip (LoC) systems are increasingly used in the areas of genomics, proteomics and drug discovery, their efficient simulation and design at system-level continue to be a challenge. Experimental trial-and-error and multiphysics-based high fidelity computation [...]

Simulation of Electrokinetic Flow and Analyte Transport in Nano Channels

Feng J.J., Krishnamoorthy S., Wang G.W., Sundaram S., CFD Research Corporation, US

This paper demonstrates the electrokinetic flow and transport of charged and neutral analytes in nanochannels by solving full system of governing Poisson-Nernst-Planck equations without any assumptions. The issues related to the spatial and time scales [...]