Implantation of Langerhans islet in alginate shell is an alternative for the treatment of diabetes type 1. Finding an adapted process for cell encapsulation is a challenge. The process must product spherical and monodisperse capsules [...]
In this work we present an all-polymer chip for measuring exocytotic release from neuronal cells using electrochemical sensing at a conductive polymer microelectrode. This chip combines several novel aspects, such as the use of conductive [...]
, Gajjeraman S.
, Hao N.
, Kalkat H.
, Lin F.
, Ma X.
, Nandagopal S.
, Tian G.
, Wadhawan N.
, Xiang B.
, Zhang M.
, University of Manitoba, CA
Microfluidic devices provide powerful new tools for quantitative stem cell research owing to its advantages in cellular microenvironmental control and experiment throughput over conventional methods. Particularly, microfluidics is playing a growing role in studying stem [...]
The ability to precisely trap, transport and manipulate micrometer-sized objects is very important in microfluidic applications. Caenorhabditis elegans (C. elegans) is one of the most commonly used animals in biological and medical research due to [...]
Sperm motility analysis is a representative method for evaluation of male fertility, since motility correlates with viability. The conventional method, commonly referred to as Computer-Assisted Sperm Analysis (CASA), to records motility and linear velocity (LV) [...]
Instability of steady-state conduction of a fluid in an annulus between two concentric circular cylinders subjected to charge injection either from the inner or outer and from both cylinder electrodes is considered. The results given [...]
Here we propose two different ways to generate either monodisperse microemulsions or monodisperse microbubbles. With the first of these techniques a jet is formed with the same type of cone-jet geometry predicted by the numerical [...]
At microscale, an efficient mixing is a keystep which dramatically accelerates bio-reactions. This paper presents an experimental and theoretical study of electrothermal chaotic mixing. To do so, asymmetric vortices are blinked to perform time dependant [...]
The transport of charged particles and water through nanofluidic pores is governed by the concentration, potential and pressure gradients. Better understanding of the interplay of these forces, of the resulting fluxes of charged particles and [...]
In this work, we use a commercial finite element software, Comsol Multiphsics to solve some squeeze-film damping problems, which were experimentally investigated in the literature. They involve rotational motion at both high and low pressure [...]
The human eye is a highly complex organ that consists of multiple different tissues with different properties and functionality, as well as pressurized fluid compartments with limited flow. Owing to this complexity, there are many [...]
Realistic modeling of biomolecules near amorphous silica (“glass”), a material commonly used for biomedical device fabrication, is required for device design and evaluation. Our potential model, based on ab initio quantum chemical calculations, is designed [...]
Ethylene glycol-based nanofluids containing silicon carbide (SiC) in the concentrations 0.1, 1 and 5 wt% were characterized, in order to understand their potentiality to improve the heat transfer efficiency of the base fluid. Measurements performed [...]
Nanofluids are stable colloidal suspensions of nanoparticles, nanofibers, or nanocomposites in common base fluids, These nanofluids can possess properties that are substantially different from their parent materials. Study on nanofluids heat transfer is rather a [...]
Nanofluids, dispersed nanoparticles in base fluid, have been drawing the attention as heat transfer fluid for enhancement of critical heat flux (CHF). The enhancement of CHF contributes to increase the safety margin of thermal system. [...]
In this work, we have carried out an intensive experimental study on the manipulations of micro magnetic particle chains under vibrating magnetic fields. The chain is firstly formed by a uniform directional field, and then [...]
Mixing of liquid samples in microfluidic systems has attracted many researchers mainly due to small characteristic dimensions of these channels, absence of turbulence and small diffusion coefficients. Depending on the mode of operation, different realizations [...]
Unlike traditional microchannel-based microfluidics, free-surface microfluidics features no channel, ease to clean, simple design fabrication and operation, as well as external access to the samples. It has been proven that free-surface droplets can be actuated [...]
We present a polymer-based microfluidic chip which has deposited carbon nanotubes (CNTs) onto the microchannel. The chip is capable of performing DNA preparation process like restriction enzyme digestion and ligation of DNA. The advantage of [...]
This paper presents a detailed study for the effects of different types of solvents on dissolution of photoresist inside the parylene micro-channels, for the first time. Experimental results indicate that photoresist dissolution in dipolar aprotic [...]
This work demonstrates a novel all-in-polymer device for single cell capture applicable for biological recordings. The chip is injection molded and comprises a “cornered” (non planar) aperture. Zanetti et al. have reported that mammalian cells [...]
A nanoposts array was fabricated on a PMMA based nanofluidic chip by nanoimprinting lithography. The electrophoresis of Lambda and T4 DNA in the nanoposts was studied. A periodical stretching and recoiling motion was observed. Each [...]
Manipulation and analysis of individual cells is key in understanding processes that control single-cell behavior in complex environment. Nanotechnology-based tools having high sensitivity and low invasiveness are holding great promises as new biomedical devices for [...]
Real-time monitoring of liquid’s viscosity has significant impacts on many areas such as medicine, biology and petrochemistry. However, most existing sensors have complicated fabrication and testing processes and are not truly compatible with fluidic systems [...]
Recent work has demonstrated that while nanofluids do indeed exhibit increased heat transfer properties , there is no abnormal enhancement as had been claimed by early proponents of nanofluids. However, this lack of abnormal enhancement [...]
Circulating tumor cells (CTCs) are metastatic cells that are detached from a tumor and are found in the blood of cancer patients. The presence of CTCs in the blood indicates the metastatic stage of cancer, [...]
Micro direct alcohol fuel cell, a type of micro fuel cell, is an alternative energy resource which generates electricity without fuel combusting. The micro fuel cell normally contains three parts of microchannels, electrodes, and membrane. [...]
Microfluidics applications can benefit from a dry film approach in multiple ways – particularly in the preparation of multi-layer, multi-level fluidic channels and structures on patternable substrates and covers. In addition, polymer microreactors and other [...]
Applications of magnetic particles have grown dramatically in recent years, especially for emerging microfluidic applications in the fields of microbiology, nanomedicine and biotechnology where they are commonly used to sort and separate biomaterials. Magnetic particles [...]
Mechanisms of nanoparticle (NP) and microparticle (MP) transport in confined spaces and role of material properties are not clearly understood, and transport models may not be complete. Here we present recently developed models of convective [...]
The electric properties of human blood is vital. This is normal because this viable fluid have huge quantity of unexplored domains about its properties. For example, only few authors have examined the correlation between the [...]
It was shown that in an ideal non-conducting magnetic nanofluid with frozen- in magnetization there are three types of waves: slow and fast magnetosonic waves and Alfvén -type wave. Alfvén -type wave propagating in non-conducting [...]
Suspensions of nanoparticles in liquids, known recently as “nanofluids,” have generated considerable interest for their potential to enhance the heat transfer in thermal systems, and reduce the possibility of erosion, sedimentation and clogging that plagued [...]
Journal: TechConnect Briefs
Volume: 2, Nanotechnology 2012: Electronics, Devices, Fabrication, MEMS, Fluidics and Computational (Volume 2)
Published: June 18, 2012
Industry sectors: Advanced Materials & Manufacturing | Sensors, MEMS, Electronics
Topics: Micro & Bio Fluidics, Lab-on-Chip