Ferrari M. – TechConnect Briefs

Interfacial effects and diffusion transport regimes in nanofluidic systems

Ziemys A., Milosevic M., Ferrari M., Kojic M., The Methodist Hospital Research Institute, US

Because the Peclet number is very small for nanofluidic systems, diffusion may be at least as important as the active mass transport. In nanoscale solid surfaces may alter fluid properties and diffusion at interface. Here, [...]

Nanoparticle transport models in confined fluids

Mahadevan T.S., Kojic M., Milosevic M., Isailovic V., Filipovic N., Ferrari M., Ziemys A., The Methodist Hospital Research Institute, US

Mechanisms of nanoparticle (NP) and microparticle (MP) transport in confined spaces and role of material properties are not clearly understood, and transport models may not be complete. Here we present recently developed models of convective [...]

A “leukolike” multistage delivery system to overcome biological barriers

Qauttrocchi N., Chiappini C., Cooper L., Ferrari M., Tasciotti E., University of Texas Health Science Center, US

Delivery systems based on Nanoporous Silicon Particles (NSPs) have been proposed as ideal candidates for the targeted release of drug and contrast agents to tumor sites as porous silicon is biocompatible, biodegradable and easy to [...]

Novel mesoporous silicon particles as an efficient sustained delivery system for antibiotics

Yazdi I., Chiappini C., Weiner B., Ferrari M., Tasciotti E., The University of Texas Health Science Center at Houston, US

Delivery systems able to release antibiotics over an extended period of time can solve all these issues and provide efficacious alternative solutions to the current approaches. The ultimate objective of this study is to prove [...]

Agarose coating improves protein stability during sustained release

De Rosa E., Yadzi I., Liu X., Ferrari M., Tasciotti E., UT HSC Houston, US

The advances in drug-delivery systems over recent decades highly improved the effectiviness of drug administration. Biocompatible, biodegradable porous silicon microparticles stable can be modified to provide controlled release and enhanced stability of the loaded/encapsulated bioactive [...]

The Next Generation of Proteomic Nanochips for Biomarker Discovery

Hu Y., Tasciotti E., Bouamrani A., Liu X., Li L., Liu X., Ferrari M., The University of Texas at Austin, US

In this study, the nanoporous silica thin films (NSTF) were chosen for the reproducible fractionation and selective binding of the serum-based low molecular weight proteome (LMWP). It has been recognized that the collection of LMWP [...]