Advanced Materials & Manufacturing – Page 264

siRNA and Paclitaxel Loaded PEG-PCL-PEI Tri-block Polymeric Micelle for Gene and Chemo-therapy Applications in Multidrug-resistance cancer cell

Hsu C.Y., National Chung Hsing University, TW

An annoying problem of chemotherapy was the drug resistance of cancer cell which was expression of multidrug-resistance associated proteins and resulted in ineffective treatment. To conquer this problem, a small interfering RNA (siRNA) molecule and [...]

Synergistic effects in mixed micellization between natural and synthetic block copolymers

Portnaya I., Khalfin R., Kesselman E., Danino D., Technion – Israel Institute of Technology, IL

Amphiphilic block copolymers and mixtures of amphiphiles find broad applications in numerous nano-technologies. In our previous study, we showed that interactions between a biological charged diblock copolymer, beta-casein, and a synthetic uncharged triblock copolymer, Lutrol [...]

Characterization of rMOMP-187 Peptide Encapsulated in PLGA 50:50 Nanoparticles

Taha M., Singh S.R., Butler C., Nyairo E., Dennis V.A., Alabama State University, US

The design of an immunization regimen capable of inducing sustained genital mucosal Th1 response is the current goal for a vaccine for humans to control the severe complications of genital infection by C. trachomatis. In [...]

Synthesis and characterization of new nanoparticles formed by milk whey proteins submitted to a thermal gelation process

Lopes J.R., Coimbra J.S.R., Teixeira A.V.N.C., De Oliveira E.B., Federal University of Viçosa, BR

In this work, nanostructures formed by the two whey proteins (alpha-lactoalbumin and beta-lactoglobulin) were synthesized througha thermal gelation process. The obtained proteic nanoparticles were characterized by using dynamic light scattering, transmission electron microscopy and atomic [...]

Hybrid silica-coated palsmonic-magnetic biomarkers

Sotiriou G.A., Hirt A.M., Lozach P-Y., Teleki A., Krumeich F., Pratsinis S.E., Particle Technology Laboratory, ETH Zürich, CH

In this study, hybrid silica-coated plasmonic-magnetic nanoparticles have been synthesized in one-step by a scalable flame aerosol technology. The effect of the silica in the stability of the nanoparticles, as well as their biocompatibility are [...]

Small Photostable Photoswitchable Quantum Dots as Nanotools for Live Cell Imaging

Díaz S.A., Jovin T.M., Jares-Erijman E.A., University of Buenos Aires, CIHIDECAR, CONICET, AR

We have developed a novel surface architecture for the generation of biocompatible and stable photoswitchable quantum dots (psQDs). The system is based on Förster Resonance Energy Transfer (FRET) from a QD donor to diheteroarylethenes photochromic [...]

Phase Behavior and Macroscopic Processing of Single-Walled Carbon Nanotube – Lysozyme Dispersions

Horn D.W., Davis V.A., Auburn University, US

Lysozyme (LSZ) facilitates the dispersion of single-walled carbon nanotubes (SWNT) while maintaining its’ antibacterial activity through macroscopic processing. The structural and enzymatic nature of LSZ makes possible the dispersion of SWNT for processing into macroscopic [...]

Highly stable and orientationally coupled gold nanoparticle antibody conjugates for sensitivity improvement in LFIA

Ijeh M., Vossmeyer T., Weller H., University of Hamburg, DE

LFIAs are used in the investigation of a variety of bio-molecular binding interactions and they remain the primary means for point of care and fast detection of analytes including pathogens and toxins. In a novel [...]

Nanoskin for Medical Applications

Basmaji P., Innovatecs, BR

The present paper describes NANOSKIN production for medical applications. Nanoskin is produced from the bionanotechnology process. Nanoskin is a highly hydrated pellicle made up of a random assembly of ribbon shaped fibers less than 100 [...]

Fabrication of magnetic bio-Au nanoclusters by using SlaA-layer ghosts of Sulfolobus acidocaldarius as a template

Selenska-Pobell S., Reitz T., Geissler A., Herrmannsdörfer T., Merroun M., Forschungszentrum Dresden Rossendorf, DE

We demonstrate that the outermost proteinaceous surface layer SlaA of the thermo acidophilic archaeon Sulfolobus acidocaldarius is an excellent matrix for preparation of bio-Au nanoclusters. The archaeal bio-Au nanoparticles are significantly bigger and possess considerably [...]