Advanced Materials & Manufacturing – Page 265

RAFT Polymerisation for delivery of bioactives

The RAFT (Reverse Addition-Fragmentation chain Transfer) process is a ground breaking technology that offers unprecedented control over the composition, functionality and architecture of polymers. The versatility of the RAFT technology provides enormous potential for designing [...]

Nanoparticles co-encapsulating hVEGF and hAng-1 can induce mitotic and antiapoptotic effect on vascular endothelial cells

Khan A.A., Paul A., Abbasi S., Prakash S., McGill University, CA

This study demonstrates the combined effect of the angiogenic proteins, hVEGF and hAng-1, coencapsulated in human serum albumin (HSA) nanoparticles (NPs), towards human umbilical vein endothelial cells (HUVECs) and an evaluation of the potential application [...]

Cellulose Fiber and Nano-Fiber Composites based on Castor Oil-Polyurethane Matrix

Ansari M.N.M., Shanks R.A., Universiti Tenaga Nasional, MY

The bimodal combination of cellulose fibre dimensions resulted in complementary properties from the same chemical composition. The nano-cellulose fibers provided thixotropy to the castor oil based reactants. The composites exhibited strength, toughness and a modulus [...]

Enhanced proliferation of osteoblast cells on mechanically deformed elastic membranes

Toworfe G.K., Composto R., Ducheyne P., Regent University College of Science and Technology, GH

Proliferation of osteoblast cells is enhanced on functionalized elastically deformed membrane

Mechanistic studies of in vitro cytotoxicity of PAMAM dendrimers in mammalian cells

Mukherjee S.P., Lyng F.M., Garcia A., Davoren M., Byrne H.J., Focas Research Institute, Dublin Institute of Technology, IE

The in vitro cytotoxic response of human dermal and colon cell lines to structurally well-defined full generation cationic dendritic polyamidoamine (PAMAM) nanoparticles of generations G4, G5, G6 was investigated. PAMAM dendrimers have been demonstrated to [...]

Nanomaterials can influence living biological systems with nanometer sensitivity

Sabella S., Brunetti V., Maiorano G., Rizzello L., Sorce B., Vecchio G., Galeone A., Cingolani R., Pompa P.P., Italian Institute of Technology, IT

We show the different response of human neuroblastoma cells line to gold surfaces with different levels of nanoroughness, finding out that neurons are capable to sense and actively respond to these nanotopography features, with a [...]

Nanoviricides as Anti-Influenza Agents

Diwan A.R., Tatake J.G., Barton R.W., Menon K., Nanoviricides, Inc., US

Nanoviricides® anti-influenza agents are designed to mimic a natural host cell receptor to which all influenza A viruses bind and infect host cells. A nanoviricide is composed of a flexible polymer backbone with virus-specific ligands [...]

Biomimetic High Filler Content Composites using Bisphenol-A Ethoxy Diacrylate

Daud N., Shanks R.A., RMIT University, AU

Materials were prepared similar to nacre with its layered structure of high filler content. Nacre is based upon about 95 %·w/w calcium carbonate as a composite with a layered block structure. Nacre has high modulus, [...]

Biomimetic Polyurethanes for Regenerative Medicine

Ciardelli G., Sartori S., Serafini P., Boffito M., Caporale A., Silvestri A., Bernardi E., Boccafoschi F., Politecnico di Torino, IT

Degradable linear polyurethanes from non toxic building blocks were prepared. Bioactive peptides were incorporated in polyurethane chains, in order to create a synthetic equivalent of the Extracellular Matrix, able to mimic natural tissue. Both cell [...]

Attenuated-Affinity Biotin Analogs for Catch-and-Release with Streptavidin

Corry S., Ying L-Q, Branchaud B., Life Technologies, US

The binding between streptavin and biotin, which is one of the strongest non-covalent interactions known in nature, is used ubiquitously in molecular biology. However, when a biotinylated molecule is captured for testing purposes and cannot [...]