The biodegradable polymeric PLA-PEG nanoparticles is an efficient delivery system for a chlamydial M278 mucosal nanovaccine that provides protective systemic and mucosal antibody responses in mice

, , , , , ,
The rising concerns relating to the failure of public health programs, relying mostly on antibiotic treatments to control the plethora of disease manifestations caused by Chlamydia trachomatis in humans, strongly begs the urgency for an [...]

Sustained Release of Functional Interleukin-10 Encapsulated within Poly (lactic acid)-b-Poly (ethylene glycol) Nanoparticles Down-regulates Cytokines in Mouse Macrophages Exposed to Chlamydia trachomatis

, , , , , , ,
Inflammation which is induced by the presence of cytokines and chemokines is an integral part of Chlamydial infection. Chlamydia trachomatis (CT), the bacterial pathogen responsible for this sexually transmitted infection worldwide, causes severe inflammation including, [...]