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Investigation of Volume of Fluids (VOF) Method and System Models for Design of Microfluidic Ink Delivery Apparatus for Dip Pen Nanolithography (DPN)

Banerjee D., Texas A&M University, US
DPN™ is a versatile technology that leverages Scanning Probe Microscopy for applications in biotechnology, photomask repair, molecular-electronics, nano-electronics and mask-less lithography(1). In earlier studies (2) the DPN process was augmented for biotechnology applications (genomics, proteomics) [...]

Fast and Sensitive DNA Hybridization Through Micro- Fluidics

Marafie A.H., Madou M.J., University of California Irvine, US
The research target for DNA hybridization through micro-fluidics is to achieve a fast and very sensitive hybridization reaction by investigating the effect of different pertinent parameters using computational and experimental methods. The mathematical model that [...]

Development of Microfluidic Device for Heterogeneous Immunoassay on Polystyrene Platform with Electroosmotic Control

Pribyl M., Snita D., Marek M., Institute of Chemical Technology Prague, CZ
We have developed a microfluidic device for heterogeneous immunoassay on the polystyrene platform. The wire-imprinting method has been chosen for the construction of microchannel structure of the chip. Immunoassay based on the interaction of fluorescently [...]

Thermal Modulation and Instability of Viscous Microjets

Furlani E.P., Eastman Kodak Company, US
Liquid microjets are inherently unstable and can be broken into droplets by various means including the modulation of pressure, velocity, and/or fluid properties. In this presentation we discuss the controlled breakup of viscous microjets via [...]

An Analytical Model for the Prediction of Microdrop Extraction and Splitting in Digital Microfluidics Systems

Berthier J., Raccurt O., Clementz Ph., Jary D., Claustre P., Peponnet C., Fouillet Y., CEA-LETI, FR
In the preceding text submitted to Nanotech 2005, we have demonstrated that surface tension is the dominant force on liquid microdrops in EWOD microsystems and that the problem is mostly topological. Minimization of the surface [...]

The Application of Micro Reactors for Chemical Synthesis: How small is required?

Watts P., University of Hull, UK
Drug discovery is a very time consuming process, with one of the slowest steps being the synthesis and purification of candidates. Several companies have acknowledged that the miniaturisation of chemical reactors offer many advantages of [...]

Electrostatic Droplet Ejector with Monolithic Fabrication of Nozzle

Lee S-H., Byun D.Y., Ko H.S., Kim Y., Yang J.H., Han S.J., Son S.U., Oh J.T., Konkuk University, KR
This paper presents a novel mechanism of electrostatic micro droplet formation and ejection of fluid. Unlike conventional electrostatic jetting which requires a high operating voltage, we offer a, commercially viable, low operating voltage for droplet-on-demand [...]

Dimensioning of a New Micro-Needle for the Dispense of Drugs in Tumors and Cell Clusters

Berthier J., Rivera F., Caillat P., Berger F., CEA-LETI, FR
In medical treatment, there is a constant need to deliver active molecules into targeted cells, but this dispense is often difficult and time consuming. For example, in cancerology, it has been shown that active molecules [...]

A Computational Model for the Design of ElectroWetting On Dielectric (EWOD) Systems

Bedekar A.S., Jenkins J.W., Sundaram S., CFD Research Corporation, US
Microfluidics has enabled the development of integrated lab-on-a-chip (LoC) devices for use in a clinical diagnostics, high throughput screening, drug discovery, biodefense and environmental monitoring. Although most microfluidic devices are based on continuous flow of [...]

Inkjet Assisted Micro-Scale Cooling of Electronics

Sharma R.K., Bash C.E., Patel C.D., Hewlett Packard Co. Laboratories, US
Rise in the overall power dissipation of computer systems has posed a severe challenge for cooling microprocessors. Increases in microprocessor power dissipation and the resulting effect on the cost and complexity of thermal management solutions [...]

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