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Computational Modeling and Simulation of Microfluidic Biochips for Parallel Biomolecular Synthesis

Kan H-C, National Center for High-performance Computing, TW
In this study, a novel microfluidics based biochip has been developed by the aid of analytical modeling and numerical simulation efforts for the purpose of massively parallel oligonucleotude-DNA (oDNA) syntheses. The microfluidic biochip consists of [...]

Valving in Microchannels via Electrodeposition on Solid Electrolytes

Kozicki M.N., Maroufkhani P., Mitkova M., Arizona State University, US
We have recently developed a reliable and inexpensive way to electrically regulate flow through microchannels via a structure that can be made using readily available microfabrication techniques. We use an electrical signal to stimulate silver [...]

Characteristics of Bacterial Pumps in Microfluidic Systems

Kim M-J, Breuer K.S., Brown University, US
In this paper we show that (i) the flow-deposition of bacteria can successfully create a live bacterial carpet to generate local fluid motion inside a microfabricated system; (ii), that the carpet-activated microfluidic system can be [...]

Multiobjective Evolution Strategies for Optimization of Microfluidic Mixing

Mautner T., Consultant, Technology Development, US
microfluidics, lattice Boltzmann, opimization, biosensor Summary: An investigation has been performed to determine the effect of various surface temperature distributions on the mixing of a binary fluid. Lattice Boltzmann simulations were conducted on a binary [...]

Modeling, Analysis and Design of Centrifugal Force Driven Transient Filling Flow into Rectangular Microchannel

Kim D.S., Kwon T.H., Pohang University of Science and Technology, KR
In this paper, we first present successful modeling and analysis results of a centrifugal force driven transient filling flow into a rectangular microchannel. Two types of exact and pseudo-static approximate solutions were derived for the [...]

Design, Modelling and Simulation of a PZN-PT Actuated Micropump

Malleo D., Haas C., Kraft M., University of Southampton, Microelectronics Group, UK
We present an optimization methodology for the design of a self-priming piezoelectrically actuated pump made of a borosilicate glass bonded to silicon. New findings in the design optimization of the piezo-actuated membrane are presented: it [...]

A Novel Microrheometer for Measuring Rheological Properties of Microquantities of Fluids

Lo C.S., Prewett P.D., Ward M.C.L., Docker P.T., University of Birmingham, UK
This paper describes a novel micromachined microrheometer, designed to measure the rheological properties of micro quantities of fluids. Measurements are achieved by monitoring the movement of superparamagnetic microbeads whilst in suspension in fluid when placed [...]

The Manufacture and Preliminary Testing of a Novel Bio-MEMS Filtration Chip

Docker P.T., Prince M., Kinnell P.K., Ward M.C.L., Ma X., Birmingham University, UK
In the clinical/microbiological laboratory there are currently several ways of separating specific cells from a fluid suspension. Conventionally cells can be separated based on size, density, electrical charge, light-scattering properties, and antigenic surface properties. Separating [...]

Mechanical Behavior of Micro-Drops in EWOD Systems: drop extraction, division, motion and constraining

Berthier J., Clementz Ph., Jary D., Raccurt O., Claustre P., Peponnet C., Fouillet Y., CEA-LETI, FR
We present a novel contribution to the design of electrowetting microdevices (EWOD) by using an energy minimization approach. Altough the dynamics of motion of microdrops by electrowetting may be rapid, it is shown that, due [...]

Modular Design Approaches for MicroFluidic Systems

Gilde M.J., van den Vlekkert H., Leeuwis H., Prak A., CapiliX BV, NL
The possibilities promised by microfluidic systems have not only interested scientists, but also industries, especially in the areas of the Life Sciences (food, medical, biotech) and fine chemistry (pharma) [2]. Microfluidics is the MEMS-field in [...]

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