Biomaterials

Electrospinning of collagen with nanocapsules of PLGA for delivery of paclitaxel in drug-eluting stents

Agudelo L.M., Cornelio J.A.C., Rodriguez L.F., Ortiz I.C., Hoyos L.M., Colmenares G.J., Universidad Pontificia Bolivariana, CO

Drug-eluting stents can facilitate a drug’s release directly to the specific site, but the main difficulty with drug-eluting stents is that the initial burst of drug release can extremely affect the pharmacological action and this [...]

Microwave-assisted synthesis of bioabsorbable nanoparticles to be used as reinforcement of PLGA in biomedical applications

Colmenares G.J., Ramírez M.E., Ortiz I.C., Hoyos L.M., Universidad Pontificia Bolivariana, CO

Biodegradable polymers have been used in a large number of mass production applications such as packaging, paper coating, fibers, films and other disposable items, as well as in biomedical applications (Kalia & Avérous, 2011). The [...]

Examination of the osteoconductive, antibiofilm & biomechanical properties of a PEEK-ZEOLITE composite biomaterial for intervertebral spine fusion surgery

Sankar S., Johns D.W., Crudden J.J., Difusion Technology Inc., US

Introduction: Polyether ether ketone (PEEK), a common spine biomaterial demonstrates intrinsic inertness and hydrophobic properties, thereby resulting in an inherent susceptibility to bacterial infections and reduced fusion capacity within the intervertebral space due to fibrous [...]

Functional Multi-layered Bio-scaffold by 3D printed and Electro spun biodegradable materials

Choi H.W., Keimyung University, KR

In paper, we are presenting a novel technology for the bio-scaffold fabrication. The fabricated scaffold is composed of 3 layers which include a 3D printed PLA in middle and electro spun nanofibers of PCL+Collagen on [...]

Bioextraction technologies for bioplastic and biomass hydrolysates production

Ibrahim M.H.A., Hall E., Bioextrax AB, SE

Globally, there is an increased interest in environmentally friendly bio-based alternatives to currently used chemical processes in agriculture, medicine and industry. Microorganism and its enzymes can provide safe and cost-effective technologies for different applications. One [...]

Hydrogel-based scaffolds for tissue engineering

Joshi S., Singh S.R., Alabama State University, US

Gels or hydrogels are described as the matrix of cross-linked polymers. Hydrogels are naturally a part of the body in the form of collagen, gelatin, mucous, tear films, cartilage, vitreous humor, cornea, and tendon. The [...]

3D Printed Venous Valves, Biocompatibility and Functionality

Holmes B., Nanochon LLC, George Washington University, US

3D printing has been gaining popularity as a method of creating heart valves. However, to the best of our knowledge, no one was yet able to 3D print venous valves, particularly using cells or biocompatible [...]

Self-navigating drug delivery nanovehicles driven by polyvalent multifunctional phages and their promiscuous proteins

Petrenko V.A., Gillespie J.W., Auburn University, US

Development of precision medicines acting specifically at the site of disease has been a long sought goal for the last century, starting from pioneering works of Paul Ehrlich, who suggested the concept of site-directed chemotherapeutics [...]

Enhancement of anticancer action of traditional (doxorubicin and cisplatin) and experimental (landomycin A) drugs by their delivery in vivo with novel C60-fullerene-based nanocarriers possessing innate ROS-modulating activity

Panchuk R., Prylutska S., Skorokhyd N., Lehka L., Skivka L., Hurmach V., Evstigneev M., Piosik J., Berger W., Prylutskyy Yu., Scharff P., Stoika R., Vari S., Institute of Cell Biology NAS of Ukraine, UA

Rapid development of multi-drug resistance of tumor cells to chemotherapy caused by the over-expression of specific ABC-transporter proteins and/or multiple defects in genes involved in cell cycle and apoptosis regulation in cancer cells frequently leads [...]