Nanodelivery of Chinese traditional medicine extract of Gingko Biloba (EGb-761) induces superior neuroprotection following traumatic brain injury in heat stroke

, , , , , , , , , ,
Military personnel are often exposed to high summer heat resulting in heat stroke (HS) and related illnesses. HS often results in serious mental and physical consequences due to breakdown of the blood-brain barrier (BBB) to [...]

Co-administration of TiO2 nanowired cerebrolysin and alpha melanocyte stimulating hormone has superior neuroprotective effects on brain pathology following concussive head injury after sleep deprivation

, , , , , , , , , ,
Sleep deprivation (SD) is common in military personnel engaged in combat operations. Our previous reports show that 12 h SD alone induces brain pathology and continued until 72 h in a progressive manner. However, these [...]

Exacerbation of amyloid beta peptide and Tau protein in the cerebrospinal fluid following Traumatic Brain Injury at Hot Environment. Neuroproetction by TiO2 nanowired delivery of cerebrolysin with tau antibodies

, , , , , , , , , , , ,
Military personnel are often exposed to high environmental temperature in desert areas during combat operations. Since traumatic brain injury (TBI) is quite common in combat operation, a possibility exists that hot environment (HE) could affect [...]

TiO2-nanowired delivery of cerebrolysin thwarts exacerbation of sleep deprivation induced decline in regional brain derived neurotrophic factor, brain pathology and behavioral dysfunctions following emotional stress

, , , , , , , , , ,
Sleep deprivation (SD) is a serious problem in military personnel during combat operations. Normally they have only a few hours of sleep under severe stressful conditions. This leads to profound mental and cognitive dysfunctions. Previous [...]

Nanodelivery of cerebrolysin reduces depressive stress induced exacerbation of Alzheimer’s disease brain pathology following amyloid-beta peptide infusion

, , , , , , , , , ,
Military personnel are highly vulnerable to Alzheimer’s disease (AD). This is because of the fact that severe stress of trauma, sleep deprivation or combat stress causes increased deposition of amyloid beta peptide in the cerebrospinal [...]

Nanodelivery of cerebrolysin reduces functionalized Gold Nanoparticles induced Blood-brain barrier disruption, brain edema formation and brain pathology

, , , , , , , , , , ,
Recently, gold nanoparticles (AuNPs) are used for drug delivery in treating several neurological disorders e.g., Alzheimer’s disease (AD), Parkinson’s disease, Stroke and trauma. In addition, use of AuNPs for diagnostic purposes in various diseases are [...]