Papers – Page 62 – TechConnect Briefs

CFD analysis of particle magnetophoresis in multiphase continuous-flow bioseparators

Gómez-Pastora J., Karampelas I.H., Bringas E., Furlani E.P., Ortiz I., University of Cantabria, ES

The use of magnetic particles has recently expanded for a process known as detoxification in which different toxins and microorganisms are captured from the bloodstream of septic patients. Magnetic particle-based detoxification has been successfully applied [...]

Numerical Investigation Of Rigid Microparticles Dynamics: Aggregation And Clogging Phenomena In Microfluidics By Discrete Element Method (DEM) And CFD Coupling

Shahzad K., Van Aeken W., Kamyab V.K., Mottaghi M., Kuhn S., KU Leuven, BE

Microfluidics has achieved a positive response in the industrial sector in the last two decades, i.e., due to its minute size plus control over all the chemical and physical properties at various flow rates (Re~1-10) [...]

On the use of Zisman’s function for the determination of the velocity of spontaneous capillary microflows

Berthier E., Berthier J., Lee Jing, Gosselin D., Navarro F., Berthier E., Berthier J., Theberge A., CEA-LETI, FR

Capillary-based microfluidic systems are increasingly used in the fields of biotechnology, medicine, thermics, energy and space. In such systems the energy source responsible for the flow is the surface energy of the walls. Extending the [...]

Low-cost screen printed and embossed LAMP micro-reactors

Gosselin D., Gougis M., Baque M., Maffini-Alvaro V., Mailley P., Bourdat A.G., Vignoud S., Navarro F., Belgacem M.N., Chaussy D., Berthier J., CEA-Grenoble, FR

Introduction: Diagnostic is probably the most important step in the fight against infectious diseases and epidemics. While it is necessary to give a treatment to diseased people, it is just as important to give the [...]

Design and development of Microfluidic Platform for Water Analysis

Grover S., Deshpande A., Ravindran T., Krishnan J.N., BITS Pilani, K. K. Birla Goa Campus, IN

Simple, cost- effective water analysis facilities are essential in developing countries like India [1]. Heavy metal ion contamination is one of the major causes of chemical pollution [2], like many rivers in India. In general, [...]

Two-Dimensional Analysis of the Enhanced Magnetic Bioseparation in Microfluidic Systems

Shi Z., Sun J., Jia S., Zhang P., Xi'an Jiaotong University, CN

The separation of magnetically-labeled bioparticles in a microfluidic system is dependent on the characteristics of the particles and the carrier fluid as well as the external magnetic field. To discuss the influence of these factors, [...]

3-D electrode configuration for electrochemical impedance spectroscopy of bulk solution

Wang A., Koh D., Schneider P., Oh K.W., University at Buffalo, US

Abstract In this paper, a 3-D electrode configuration for electrochemical impedance spectroscopy (EIS) of a bulk solution was studied. Top- and bottom- electrode configuration, where two electrodes sandwich the sensing channel, was fabricated using the [...]

Deterministic Lateral Displacement (DLD): Finite element modeling and experimental validation for particle trajectory and separation

Pariset E., Berthier J., Révol-Cavalier F., Pudda C., Gosselin D., Navarro F., Icard B., Agache V., CEA-LETI, FR

In biotechnology and biology, deterministic lateral displacement (DLD) arrays are used to separate particles based on their size, such as cells, bacteria, parasites and exosomes. DLD is very promising for sample preparation purposes as it [...]

On the use of polymeric additives to promote plasma separation from whole blood in open microchannels

Lee E., Berthier J., Laurent P., Navarro F., Cubizolles M., CEA, FR

Polymers additives in whole blood are known to modify blood physical properties. For example, Dextran molecules usually accelerate the aggregation of re-suspended RBCs in Ringer solutions. In this work, we first investigate the effect of [...]

Self-navigating drug delivery nanovehicles driven by polyvalent multifunctional phages and their promiscuous proteins

Petrenko V.A., Gillespie J.W., Auburn University, US

Development of precision medicines acting specifically at the site of disease has been a long sought goal for the last century, starting from pioneering works of Paul Ehrlich, who suggested the concept of site-directed chemotherapeutics [...]