Papers – Page 236 – TechConnect Briefs

Nanoherbal antiseptic medicine/ bandage for effective and safe treatment of external wounds

Tahir L., Nazir R., Khan N., Pakistan Council Of Scientific and Industrial Research, PK

Use of different antibiotics and bactericides in treatment of wounds has resulted in several side effects together with development of resistant bacterial strains. The need is to develop safe and new route for the treatment [...]

‘Sink effect’ of dually-decorated nanoliposomes on Abeta clearance

Re F., Minniti S., Bana L., Masserini M., Re F., University Milano Bicocca, IT

Plaques containing beta-amyloid peptides are one of the hallmarks of Alzheimer’s disease (AD) and the reduction of Abeta is considered a primary therapeutic target. Recently, strategies have been employed to reduce Abeta brain levels and [...]

Poly-Vinyl Pyrrolidone (PVP)-coated Silver (Ag) Nanoparticles (Ag-PVP): a Potential to Regulate Chlamydia trachomatis Inflammation

Yilma A.N., Singh S.R., Dixit S., Hidat G.G., Dennis V.A., Alabama State University, US

Chlamydia trachomatis is an important cause of sexually transmitted infection that can manifest itself as either acute cervicitis, pelvic inflammatory disease, and more commonly as a chronic asymptomatic infection. Previously we reported Ag-PVP (5-10 nm) [...]

A better biomaterial for bone regeneration: type II collagen

Tsai Y-H, Taipei Medical University, TW

Type II collagen facilitates osteogenesis and suppresses adipogenesis simultaneously during early stage of MSC differentiation, mediated through the same signaling cascades. Type II collagen-coated plates enhanced BMSC mineralization better than did either non-coated or type [...]

NAD-Nanoparticles for Therapy and Diagnosis of Alzheimer Disease

Masserini M., Gregori M., Salvati E., Re F., Masserini M., University Milano Bicocca, IT

NAD project (large cooperative; 19 partners, funded by the E.C.) is aiming to the therapy and diagnosis, even combined, of Alzheimer Disease, by synthesis of multiple-functionalized nanoparticles, able to bind, detect and remove Abeta from [...]

Gold-based Nanostructures for Improved Cancer Therapeutics

Yang C., Neshatian M., Hegarty N., Chithrani D., Ryerson University, CA

The field of nanotechnology is currently undergoing explosive development on many fronts. The technology is expected to generate innovations and play a critical role in cancer therapeutics. Among other nanoparticle (NP) systems, there has been [...]

Lysozyme – alginate nanocomplex: Effect of alginate composition

Fuenzalida J.P., Nareddy P.K., Moreno-Villoslada I., Moerschbacher B., Swamy M.J., Goycoolea F.M.A., Westfälische Wilhelms-Universität Münster, DE

In the present work we investigated the electrostatic self-assembly of nanoparticles of Lyz and different alginates (Alg A Mw~4kD and M/G~1.42 or Alg B Mw~7kD and M/G~5.00)to establish a relationship between the alginate structure and [...]

Epidermal Growth Factor-Ferritin H-Chain Nanoparticles as Nanocarrier of

Huang Y., Chen X., Cao X., East China University of Science and Technology, CN

The emergence of drug-resistant cancer cells together with the toxicity side effect of chemotherapy agents are the major obstacle in cancer treatment. We focused on providing a new pattern of protein-based nanoparticle as drug delivery [...]

Cationic lipid nanoemulsions for RNAi screening

Bruniaux J., Sulpice E., Mittler F., Texier I., Gidrol X., Navarro F.P., CEA/LETI/MINATEC, FR

Since the discovery of RNA interference, many efforts have been made to broaden perspectives of small interfering RNA (siRNA) in research and clinical work. siRNA shows a specific and effective gene silencing activity through a [...]

Commercializing unique nanoparticle-imaging-delivery platform technology for enhanced cancer therapy

Fu A., NVIGEN, Inc., US

In this presentation, we will talk about a unique nanoparticle-imaging-delivery platform developed at NVIGEN, Inc. for enhanced cancer therapeutic applications. Our proprietary nanoparticle-imaging-delivery (NID™) technology is a hybrid platform comprised of an intrinsically signal-generating component [...]