Enhancement of anticancer action of traditional (doxorubicin and cisplatin) and experimental (landomycin A) drugs by their delivery in vivo with novel C60-fullerene-based nanocarriers possessing innate ROS-modulating activity

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Rapid development of multi-drug resistance of tumor cells to chemotherapy caused by the over-expression of specific ABC-transporter proteins and/or multiple defects in genes involved in cell cycle and apoptosis regulation in cancer cells frequently leads [...]

Preparation of ion group functionalized diblock copolymers and examination of their thermogelling properties

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To investigate thermogelling behavior, in this study, methoxy polyethylene glycol-b-[poly(ε-caprolactone)-ran-poly(6-chloride-ε-caprolactone) (PCL-ran-PfCL)] (PCL-Cl) diblock copolymers were designed such that the PfCL content in the PCL segment was varied. The PCL-Cl diblock copolymers were derivatized by introducing [...]

Preparation of ion group functionalized diblock copolymers and examination of their thermogelling properties

, , , , , , , ,
To investigate thermogelling behavior, in this study, methoxy polyethylene glycol-b-[poly(ε-caprolactone)-ran-poly(6-chloride-ε-caprolactone) (PCL-ran-PfCL)] (PCL-Cl) diblock copolymers were designed such that the PfCL content in the PCL segment was varied. The PCL-Cl diblock copolymers were derivatized by introducing [...]