Papers:
Quantifying the origin of nanosilver ions and their antibacterial activity
Sotiriou G.A., Meyer A., Knijnenburg J., Panke S., Pratsinis S.E., Particle Technology Laboratory, ETH Zürich, CH
Nanosilver is prominent in nanotechnology products [1]. Concerns however about leached Ag ions from its surface into aquatic environments have challenged its broad use. The origin of these ions is explored here by conditioning the [...]
Nanomaterial Registry: An authoritative resource for assessing environmental and biological interactions of nanomaterials
Assessing the interactions of nanomaterials with environmental and biological systems is both complex and rapidly evolving. The complexity of these interactions arises from the fact that they are not only a function of the system [...]
Uptake and Elimination Behaviors of Polyethyleneimine (PEI)-Coated Multi-Walled Carbon Nanotubes by Eisenia Foetida and Daphnia Magna
Petersen E.J., Pinto R.A., Mai D.J., Landrum P.F., Zhang L., Huang Q., Shi X., Weber Jr W.J., National Institute of Standards and Technology, US
Hyphenated mass spectrometry (gas chromatography/mass spectrometry) techniques have been employed as one of the primary analytical tools for investigating the effects of ionizing radiation, chemical/biological carcinogens and oxygen derived free radicals on the induction and [...]
An investigation on the aggregation phenomena of Titanium dioxide nanoparticles in natural waters: role of ionic strength, organic matter and natural colloidal particles
Romanello M., Luppi V.A., Bertini L., Fidalgo de Cortalezzi M., Instituto Tecnológico de Buenos Aires, AR
The aggregation behavior of TiO2 nanoparticles under conditions normally encountered in natural waters was investigated. Aggregation kinetics and size distribution was determined by DLS using a Nanosizer ZS, Malvern, UK. SEM images were also collected. [...]
Antibacterial activity and intracellular accumulation of silver nanoparticles on Escherichia coli K-12
Choi Y.J., Lee B.-T., Kim K.W., Chung K.H., Song W.K., Gwangju Institute of Science and Technology, KR
We exposed Escherichia coli K-12 to engineered silver nanoparticles (AgNPs) on to understand the antibacterial activities of AgNPs. Optical density measurement by UV-Vis was used to determine the growth inhibition of AgNPs and silver ions. [...]
Molecular modeling of the PEGylated bilayer as a model for the PEGylated liposome surface in the bloodstream
The criteria for effectiveness of drug delivery liposomes (DDLs) are structural stability, site specific targeting, and lifetime in the bloodstream. Often to increase the lifetime in bloodstream DDL is coated with poly ethylene glycol (PEG). [...]
Cytotoxicity of silver nanoparticles
Sotiriou G.A., Pratsinis A., Pratsinis S.E., Leroux J.-C., Pratsinis A., Pratsinis S.E., Particle Technology Laboratory, ETH Zürich, CH
Silver nanoparticles are receiving more and more attention for their plasmonic colors and their antibacterial effects [1]. The addition of a nanothin SiO2 shell minimizes the release of toxic Ag ions and the contact of [...]
Novel Approach using SWCNT as a Mechanism of Toxicity on Fungal and Bacterial Cells
The overall goal of this project was to characterize the potential use of SWNTs as an effective alternative to present antimicrobial agents in dealing with drug-resistance. In this study, we look at possible mechanisms to [...]
Multimedia Environmental Distribution of Nanomaterials
In the present study, a generalized model of the multimedia environmental distribution of engineered nanomaterial is developed via multimedia fate and transport modeling to estimate potential exposure levels in various environmental compartments. In this model, [...]
Tools and Approaches for the Assessment of Nanomaterial Induced Oxidative DNA Damage
Petersen E.J., Marquis B.J., Jaruga P., Dizdaroglu M., Nelson B.C., National Institute of Standards and Technology, US
Determining the effects of various surface coatings on carbon nanotubes (CNTs) is critical given the numerous expected applications of CNTs and their inevitable release into ecosystems. To explore the potential ecotoxicological effects of CNT surface [...]
Novel Immune Biosensors Based on the Structured Nano-Porous Silicon for Control of Mycotoxins in Environmental Objects
Starodub N.F., Slishek N.F., Pylypenko I.V., Pylypenko L.N., Pylypenko I.V., Pylypenko L.N., National University of Life and Environmental Sciences of Ukraine, UA
To meet all the requirements of practice in respect of high sensitivity of analysis of mycotoxins as well as simplicity, cheapness and rapidity of its currying out we propose to use of structured nano-porous silicon [...]
Assessment of release and toxicity of NP from silicon-based polymer composites in a life cycle perspective
Nanomaterial integration in public domain raises concerns regarding human health impact. This study examines the possibility of nanoparticle release from new engineered nanocomposites, using real life scenarios in life cycle analysis approach. Physical and biological [...]
The Effect of Photolysis on the Stability and Toxicity of Silver Nanoparticles
The objective of this study was to determine the effect of solar irradiation on the aggregation kinetics and toxicity of a 50 nm silver nanoparticle capped with two different stabilization agents (polyvinylpyrrolidone (PVP) and citrate). [...]
A safer formulation concept for flame-generated engineered nanomaterials
Gass S., Pyrgiotakis G., Cohen J.M., Sotiriou G.A., Pratsinis S.E., Demokritou P., Harvard School of Public Health, US
Engineering less toxic ENMs that maintain valuable functional properties is crucial to the sustainability of the nanotech industry. Core-shell nanoparticles are particularly interesting in this regard. They exhibit the surface properties of their shells while [...]
Toxicological effects of functionalized single-walled carbon nanotubes (SWCNTs) on embryonic zebrafish (Danio rerio)
Since their discovery in 1993, single-walled carbon nanotubes (SWCNTs) have played an integral role in nanotechnology and have been extensively studied due to their unique structural, electrical and mechanical properties. Chemical functionalization and coating of [...]
Evidence for a direct interaction between poly-dispersed single-wall carbon nanotubes and murine erythrocytes resulting in in vitro and in vivo cytotoxicity
Single wall Carbon Nanotubes (SWCNTs) are highly hydrophobic in nature and agglomerate strongly. Treatment of SWCNTs with sulphuric and nitric acid (acid functionalization) results in the introduction of carboxy and sulfonate groups on SWCNTs and [...]
Evaluating safety and stability of CNT nanocomposites exposed to environmental conditions
There is a growing interest in the development of nanocomposites consisting of organic polymers and various nanomaterials. These materials can provide unique functionalities as compared to unmodified polymers in terms of dielectric behavior, thermal and [...]
Cytotoxic Effects of Short Multi-Wall Carbon Nanotubes in Dorsal Root Ganglion (DRG) Neurons
Because of their unique physico-chemical properties, carbon nanotubes (CNTs) have found their way into diverse industrial and biomedical applications. Their escalating uses in multiple industries result in enhanced occupational human exposure to CNTs. However, the [...]
Cytotoxicity of Magnesium Oxide Nanoparticles in Schwann Cells
Idikuda V.K., Jaiswal A.R., Wong Y.Y.W., Bhushan A., Leung S.W., Lai J.C.K., Idaho State University, US
Diverse applications of metal oxide nanoparticles in various industries have been accelerating in the last decade. Magnesium oxide (MgO) nanoparticles have been employed in ceramics, and as adhesive and additive in chemical raw materials, leading [...]
Cytotoxic Effects of Four Metallic Oxide Nanoparticles on Dorsal Root Ganglion (DRG) Neurons
Metallic oxide nanoparticles have diverse industrial applications because of their exploitable physico-chemical and other properties. Consequently, the occupational environmental exposure of humans to these nanparticles is increasing; however, the health impact of their exposure has [...]
Fungicidal nanoparticles of low toxicity from cationic lipid and polyelectrolytes
The assembly of the cationic lipid dioctadecyldimethylammonium bromide (DODAB) and polyelectrolytes such as carboxymethylcellulose (CMC) and polydiallyldimethylammonium chloride (PDDA) produced bactericidal nanoparticles in complete absence of antibiotics. In this work, these nanoparticles are evaluated regarding [...]
Cancer cell targeting of lipid gene vectors by protein corona
Caracciolo G., Pozzi D., Capriotti A.L., Cavaliere C., Cardarelli F., Bifone A., Laganà A., Sapienza University of Rome, IT
We investigated the compositional evolution of the protein corona of 1,2-dioleoyl-3-trimethylammonium propane (DOTAP) cationic liposomes (CLs) that efficiently deliver DNA in a wide variety of cell lines as a function of increasing human plasma (HP) [...]
Characterization of a Vortex Shaking Method for Producing Airborne Glass Fibers for Toxicology Studies
Current fiber measurement techniques arose primarily due to health concerns over asbestos exposure. Fiber toxicity appears to be mostly a function of fiber concentration, dimensions (diameter and length) and durability in the lungs. A fiber [...]
A Regulator’s Approach to Nanomaterials
Policymakers and regulators appear to have a mistaken belief that a singular overarching definition of “engineered nanomaterials” is a requirement for any possible regulatory strategy. Previous attempts, most recently by the European Commission, have shown [...]
Transport of Nanomaterials in Complex Media
An appreciable number of researchers have analyzed both the genotoxicity and cytotoxicity of nanoparticles in biological systems, noting extensive damage to most body organs, such effects are attributed to: i) the ease of transportation to [...]
Journal: TechConnect Briefs
Volume: 3, Nanotechnology 2012: Bio Sensors, Instruments, Medical, Environment and Energy (Volume 3)
Published: June 18, 2012
Industry sectors: Advanced Materials & Manufacturing | Energy & Sustainability
Topic: Environmental Health & Safety of Nanomaterials
ISBN: 978-1-4665-6276-9