Papers:
In vivo nanotoxicology: Toxicoproteomics
Proteomics applied to nanotechnology is now emerging as an attractive tool to address the still unanswered questions dealing with nano-biointeractions and NPs-induced toxicity in living systems. The unique advantage provided by “omic” techniques (such as, [...]
Water-borne Polymeric Nanoparticles for Glutathione-Mediated Intracellular Delivery of Anticancer Drugs
A new family of water-borne, biocompatible and carboxyl-functionalized nanogels (NGs) was developed for glutathione-mediated delivery of anticancer drugs. Nanogels were generated by e-beam irradiation of aqueous solutions of a crosslinkable polymer. Molecular structure and topology [...]
Live Cell Membrane in Interaction with Antimicrobial Molecules
Molecules in the nano size scale are potentially useful as therapeutic agents due to their size since they can interact in a sophisticated way at the cellular level. Antimicrobial oligomers (AMOs) are unique as they [...]
Competitive Binding of Natural Amphiphiles to Graphene derivatives
Understanding the interaction between graphene derivatives and natural amphiphiles in biological and environmental milieu is important for the biosustainability and biocompatibility of graphene nanotechonology. Using rapid discrete molecular dynamics simulations, we systematically studied the binding [...]
A novel technique using SWCNTs to enhanced development and root growth of fig plants (Ficus carica)
The overall goal of this project is to look at possible mechanisms to explain the effects of SWCNTs in plant growth and its antimicrobial properties in order to reduce the use of harmful chemicals in [...]
Grow of stem cells on chemical-laser generated titanium cobalt shape memory alloy nanoparticles
In this research nanoparticles are fabricated using a method that is a combination of chemical and femtosecond laser ablation methods. The resulting nanoparticles are used to coat glass substrates in order to test the biocompatibility [...]
Superhydrophobic and Superhydrophilic Nanocomposite Coatings for Preventing Microbial Adhesion on Liquid Food Contact Surface
Pathogenic microbes in biofilm matrix increase the potential of cross-contamination with processed food products, subsequently resulting in food borne disease outbreaks. Prevention of bacterial adhesion on food contact surfaces will have a massive impact in [...]
Aerosol-based fabrication of modified chitosans and their application for gene transfection
Droplets containing modified chitosans were formed by collison atomization, dried to form solid particles, and collected and studied for potential use as nanocarriers (Figure 1). Modified chitosans consisted of a chitosan backbone and an additional [...]
Biomimetic Biphasic Nanocomposite Scaffold for Osteochondral Regeneration
The current work focused on the development and evaluation of a novel biomimetic biphasic nanocomposite scaffold for osteochondral interfacial tissue engineering. Tissue-specific growth factor-encapsulated nanospheres were manufactured via a wet electrospray technique and incorporated within [...]
Evaluation of F127 / chitosan hydrogel as a scaffold for bone repair
An in situ gelled scaffold for bone tissue engineering to restore the function of bone tissues is developed. The gel is comprised of Pluronic F127 and chitosan. The gelation temperature (Tgel), and viscoelastic properties and [...]
Quatsomes: vesicles formed by self-assembly of sterols and
Ferrer-Tasies L., Moreno-Calvo E., Cano-Sarabia M., Aguilella-Arzo M., Angelova A., Lesieur S., Ricart S., Faraudo J., Ventosa N., Veciana J., CSIC, ES
Thermodynamically stable nanovesicular structures are of high interest for academia and industry in a wide variety of application fields, ranging from nanomaterials preparation to nanomedicine. Here we show the ability of quaternary ammonium surfactants and [...]
Microfluidic Synthesis of Nano-Liposomal Anesthetics
Hood R.R., Kendall E.L., Vreeland W.N., Junqueira M., Finkel J.C., DeVoe D.L., University of Maryland, US
Sophisticated analytical technologies are available enabling the direct correlation of physicochemical structure to overall function and formulation attributes through generation of spatially resolved information. This presentation will cover two case studies where advanced, surface sensitive [...]
Investigations on Transmembrane Ion Channels Suspended over Porous Silicon Membranes
This article presents a batch-fabricated porous silicon membrane tool used to investigate transmembrane protein functionality in complex biological systems. We address the physical and chemical requirements fabricate the thin porous membrane, attached a lipid bilayer, [...]
Large-scale manufacturing of radiation sculptured therapeutic nanogels
Dispenza C., Grimaldi N., Sabatino M.-A., Adamo G., Rigogliuso S., Ghersi G., Università di Palermo, IT
Pulsed electron-beam irradiation of poly(N-vinyl pyrrolidone) (PVP) aqueous solutions, at relatively low energy per pulse and doses within the sterilization dose range, has led to a variety of PVP nanogels of controlled size, that can [...]
Multi-functionalizations of Mesoporous Hollow Silica Nanospheres and Their HIFU Application
High intensity focused ultrasound (HIFU), as a representative non-invasive therapeutic mode, has attracted extensive attentions among biological and medical researchers. In this report, we focused on constructing novel mesoporous hollow silica nanospheres (MHSNs) as innovative [...]
A Specific Surface-coating Peptide for Rare Earth Nanomaterials
The induction of autophagy on exposure of cells to a variety of nanoparticles represents both a safety concern and an application niche for engineered nanomaterials. Using phage display, we have discovered an 11-amino acid peptide [...]
Effects of CdTe QDs on protein structural changes
The nano-scale material, quantum dots (QDs), has been widely used in biological labels, imaging of fixed cells and tissues due to their excellent properties, such as small size, large surface area, good photostability, and negligible [...]
Chitosan-based nanomaterials for drug delivery and antibiotic-free bacterial control
Vila-Sanjurjo C., Fuenzalida J.P., Menchicchi B., Coelho D., Engwer C., Hoffman S., Pereira S., Remuñán-López C., Alonso M.J., Vidal A., Moerschbacher B., Kollenbrock S., Fetzner S., Philipp B., Goycoolea F.M., Westfaelische Wilhelms Universitaet - Muenster, DE
Research focused on chitosan (CS)-based nanostructured materials has burgeoned in the past decade or so, particularly in the biosciences and bionanotechnology fields. Chitosan characteristics (Mw and degree of acetylation), as well as the processing conditions [...]
A novel mechanism for the synthesis of ultra-purified silver nanoparticles for the use in biomedical materials
Zuniga P., Chaves J.S., Chaves S.J., Chaves J.S., Chaves S.J., Universidad de Costa Rica and Instituto Tecnologico de Costa Rica, CR
Biomedical products are regulated by high standards of purity and quality compared to those that are not going to be linked to the human body. So it is a real challenge to incorporate a nanotechnological [...]
Preparation of BSA Nanoparticles by desolvation method as a delivery system for nutraceuticals
Sadeghi R., Kalbasi A., Moosavi-Movahedi A.A., Karimi M., Kokini J., University of Illinois at Urbana-Champaign, US
The production of biocompatible nanoparticles (NPs) is one the most attractive research areas in food and drug sciences. The more the ratio of desolvating agents the bigger the particles size. The best ratio for ethanol, [...]
2D Engineering of Protein-Based Nanoparticles for cell guidance
Tatkiewicz W.I., Seras-Franzoso J., García-Fruitós E., Vazquez E., Ventosa N., Ratera I., Villaverde A., Veciana J., Institut Ciencia Materials de Barcelona (CSIC)/CIBER-BBN, ES
Cells responses, like positioning, morphological changes, proliferation and apoptosis, are the result of complex chemical, topographical and biological stimuli. Here we show the macroscopic responses of cells when nanoscale profiles made with Inclusion Bodies (IBs) [...]
Biocompatible Nanotubes as potential Nanocarriers for hydrophobic model food and drug bioactives
Sadeghi R., Kalbasi A., Moosavi-Movahedi A.A., Emam-Jomeh Z., Razavi S.H., Karimi M., Kokini J., University of Illinois at Urbana-Champaign, US
Biocompatible nanotubes (NTs) have great potential applications especially in food and drug delivery. The NTs are very interesting because they have uniform wall thickness, two open ends, different interior and exterior layers, different size and [...]
Carbon nanotubes-metal nanoparticle heterostructures embedded within stimuli-responsive hydrogel for controlled delivery applications
In this work we report a novel hybrid hydrogel by embedded complex carbon nanotube-metal nanoparticle architectures within a hydrogel network. This leads to a novel triggering mechanism for release of multiple chemical species at controlled [...]
Establishment of a Matrix for Biorecognition Reactions based on Responsive Polymeric Compounds
Fandrich A., Buller J., Wischerhoff E., Laschewsky A., Lisdat F., Technical University of Applied Sciences Wildau, DE
Thermo-responsive polymers were synthesized and covalently bound to the surface of gold electrodes. Subsequently cyclic voltammetric and impedimetric measurements with so prepared working electrodes were realised in aqueous potassium ferro-/ferricyanide solutions at different temperatures. Significant [...]
Journal: TechConnect Briefs
Volume: 3, Nanotechnology 2013: Bio Sensors, Instruments, Medical, Environment and Energy (Volume 3)
Published: May 12, 2013
Industry sectors: Advanced Materials & Manufacturing | Medical & Biotech
Topic: Biomaterials
ISBN: 978-1-4822-0586-2