Establishment of a Matrix for Biorecognition Reactions based on Responsive Polymeric Compounds

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Thermo-responsive polymers were synthesized and covalently bound to the surface of gold electrodes. Subsequently cyclic voltammetric and impedimetric measurements with so prepared working electrodes were realised in aqueous potassium ferro-/ferricyanide solutions at different temperatures. Significant changes of the temperature dependence of the voltammetric peak current and peak separation values at LCST clearly demonstrate the thermally induced phase transition. The above described electrode system is also investigated with regard to the possibility of triggering switching process due to a biorecognition reaction on the polymer surface.

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Journal: TechConnect Briefs
Volume: 3, Nanotechnology 2013: Bio Sensors, Instruments, Medical, Environment and Energy (Volume 3)
Published: May 12, 2013
Pages: 239 - 242
Industry sectors: Advanced Materials & Manufacturing | Medical & Biotech
Topics: Biomaterials
ISBN: 978-1-4822-0586-2