Papers – Page 11 – TechConnect Briefs

Point-of-Care (POC) Micro Biochip for Cancer Diagnostics

Nunna B.B., Lee E-S, New Jersey Institute of Technology, US

American cancer society stated that a total of 1,685,210 new cancer diagnosed cases out of which 595,690 deaths from cancer are expected to be reported in the United States of America in 2016. Unfortunately Cancer [...]

Amplification-free liquid biopsy by fluorescence approach

Uhd J., Taskova M., Okholm A., Astakhova K., University of Southern Denmark, DK

Diagnostics of cancer associated ctDNA, BRAF V600E, KRAS G12D and KRAS G13D respectively. By the use of modern fluorescence microscopy and fluorescently labeled mutation specific LNA/DNA probes. Which resulted in a mutation specific detection.

Positively charged Ag-dendron conjugates: Stability enhanced AgNPs for biomedical applications

Cho T.J., Liu J., Hackley V.A., National Institute of Standards and Technology, US

We developed positively charged silver nanoparticles ([Ag-Ds]+), nominally 20 nm in diameter, using dendron chemistry combined with reduction of silver nitrate in the presence of sodium borohydride. The conjugate was developed within the context of [...]

Application of a Next Generation Hand Held Antimicrobial Cold Plasma Technology

Kim H., Izadjoo M., Izadjoo S., Marcel V., Truong H., Izadjoo M., Izadjoo S., Trideum Biociences and ChiScan LLC, US

Due to emergence of antibiotic and multi-drug resistant infectious agents, there is a growing need for development of novel and effective antimicrobial therapeutics and devices. Innovative anti-infective treatment modalities, particularly for multi-drug resistant infections and [...]

miRNA Expression Analysis in HEp-2 Cells after Gold Nanorod Application

Montgomery A., Bawage S., Chaudhary A., Singh S.R., Vig K., Alabama State University, US

Gold Nanoparticles are popular because of their use in drug delivery and other biomedical applications. However, not much is known about their toxicity. The purpose of the present study was to evaluate the toxicity of [...]

DEVELOPMENT OF SUSTAIN RELEASE POVIDONE IODINE OPHTHALMIC DROP THROUGH NOVEL IN-SITU GEL FORMULATION

Wei G., Gao X., Li X., Liang B., Lu Y., Baldwin J.J., Liang B., IVIEW Therapeutics Inc., US

Acute conjunctivitis (“pink eye”) is one of the most common and most contagious ocular infections seen in the United States, Japan and Europe. There are 5.9 million cases of infectious conjunctivitis annually in the United [...]

Bilayer coated ureteral stent as drug delivery platform to treat ureteric diseases

Lim W., Xiong G.M., Chong T.W., Huang Y., Venkatraman S., Nanyang Technological University, SG

The current methods of treating ureteric diseases such as strictures and carcinoma include endoscopic full-thickness incision of the ureteric wall and placement of an indwelling stent for up to 6 weeks. However, such interventions are [...]

TiO2-nanowired delivery of cerebrolysin thwarts exacerbation of sleep deprivation induced decline in regional brain derived neurotrophic factor, brain pathology and behavioral dysfunctions following emotional stress

Sharma A., Sharma H.S., Muresanu D.F., Lafuente J.V., Nozari A., Patnaik R., Ozkizilcik A., Tian Z.R., Mössler H., Sharma A., Sharma H.S., Uppsala University, SE

Sleep deprivation (SD) is a serious problem in military personnel during combat operations. Normally they have only a few hours of sleep under severe stressful conditions. This leads to profound mental and cognitive dysfunctions. Previous [...]

Neuroprotective effects of cerebrolysin in exacerbation of blood-brain barrier breakdown, neuropathology and upregulation of nitric oxide synthase and hemeoxygenase in diabetes and hypertension after heat stroke

Muresanu D.F., Sharma A., Sharma H.S., Lafuente J.V., Nozari A., Patnaik R., Ozkizilcik A., Tian Z.R., Mössler H., Sharma A., Sharma H.S., Iuliu Hatieganu University of Medicine and Pharmacy, RO

Military personnel are often exposed to heat stress in desert areas either during peacekeeping or combat operations. In such situations, they are quite vulnerable to heat stroke and brain pathology. Due to severe work stress [...]

Novel Nano-biomaterials for Inhibition of Respiratory Syncytial Virus

Joshi S., Kirby D., Perrie Y., Singh S.R., Alabama State University, US

The liposomes were prepared using the conventional thin film hydration method with and without peptide RF-482. The loading of RF-482 was determined using BCA assay and the RSV inhibition was studied using immune-fluorescence imaging, plaque [...]