fluorescence imaging – TechConnect Briefs

Surface Modification and Characterization of Polylactic Acid (PLA) 3D printed structures for Cell culture applications.

Pokharna P., Ghantasala M., Rozhkova E., Western Michigan University, US

The main aim of this research is to understand the surface modification effects and improve the surface properties of 3D printed scaffolds that would be biocompatible and support the growth and proliferation of cells. Polylactic [...]

Lipid nanoparticles: tumor-targeting nanocargos for drug and contrast agent delivery

Delmas T., Navarro F., Gravier J., Thomann J.S., Heinrich E., Mérian J., Fraichard A., Boisgard R., Tavitian B., Dufort S., Coll J.L., Bibette J., Boisseau P., Couffin A.C., Texier I., CEA-Grenoble, FR

A new technology for the encapsulation of lipophilic molecules -both drugs and contrast agents dedicated to chemotherapy, phototherapy, or fluorescence imaging in oncology- has been developed, based on oil-in-water nanoemulsions. Thorough physico-chemical characterizations of the [...]

Nanoconjugates of poly(malic acid) with functional modules for drug delivery

Ljubimova J.Y., Fujita M., Lee B-S, Khazenzon N.M., Wachsmann-Hogiu S., Farkas D.L., Black K.L., Holler E., Cedars-Sinai Medical Center, US

Nanoconjugates of β-poly(L-malic acid) (PMLA) have been synthesized with modules active in drug delivery, drug release, blocking of tumor-affiliated mRNA by antisense oligonucleotides, penetration of blood and cellular barriers, tissue targeting, membrane permeation, fluorescence, and [...]