Lee B-S – TechConnect Briefs

Electrohydrodynamic Micro-droplet Generation on Both Conducting and Non-conducting Surfaces by Electric Induction

Lee B-S, Lee J-G, Lee B-S, Lee J-G, Cho H.-J., Huh N., Ko C., Samsung Advanced Institute of Technology, KR

There is a rapid growing need of the drop-based delivery of small quantities of bio-functional materials, such as cells. We report a brand-new printing method to generate a single droplet in the range of pL [...]

One-step Target Protein detection from Whole Blood in a Lab-on-a-Disc

Lee B-S, Lee J-G, Lee J.N., Lee B-S, Lee J-G, Lee J.N., Lee B-S, Lee J-G, Lee J.N., Park J.M., Cho Y-K, Kim S., Ko C., Samsung Advanced Institute of Technology, KR

We report a fully integrated, one-step Lab-on-a-Disc for detecting target protein from whole blood utilizing centrifugal microfluidics, so called “Immunoassay Lab-on-a-Disc”. The design principle is the microbead-based sandwich ELISA on the Disc. The microbeads are [...]

Multifunctional Microvalves Control by Optical Illumination on Nanoheaters and its Application in Centrifugal Microfluidic Devices

Park J.M., Cho Y-K, Lee B-S, Lee J-G, Lee B-S, Lee J-G, Ko C., Samsung Advanced Institute of Technology, KR

We report ultrafast control of phase-change based microvalves utilizing nanoheaters; ferronanoparticles dispersed in paraffin wax, and heating by optical illumination using a 808 nm laser diode. High speed camera images showed that the actual response [...]

Development of Nanoconjugate with Different Monoclonal Antibodies to Inhibit Molecular Targets Important for Tumor Angiogenesis

Fujita M., Khazenzon N.M., Lee B-S, Holler E., Black K.L., Ljubimova J.Y., Cedars-Sinai Medical Center, US

Tumor cell-specific drug targeting is the major goal of nanotechnology-based platforms. A nanoconjugate Polycefin was synthesized for targeted delivery of antisense oligonucleotides and antibodies into tumors. The delivery of antisense oligonucleotides to α4 and β1 [...]

One-step Pathogen Specific DNA Extraction from Whole Blood On a Centrifugal Microfluidic Device

Cho Y-K, Lee B-S, Lee J-G, Lee Y., Park J.M., Lee B-S, Lee J-G, Lee Y., Lee B-S, Lee J-G, Lee Y., Ko C., Samsung Advanced Institute of Technology, KR

We report a fully integrated pathogen specific DNA extraction device utilizing centrifugal microfluidics on a polymer based CD platform. Using the innovative Laser Irradiated Ferrowax Microvalves (LIFM) together with the rapid cell lysis method using [...]

Three-Dimensional Simulation of Polysilicon Thin Film Transistors with Single-, Double-, and Surrounding-Gate Structures

Li Y., Lee B-S, National Chiao Tung University, TW

Thin-film-transistors (TFTs) with high mobility and low leakage current are desirable in many applications especially in liquid crystal display (LCD).We have computationally analyzed electrical properties of thin film transistors using three-dimensional (3D) simulation. It is [...]

Nanoconjugates of poly(malic acid) with functional modules for drug delivery

Ljubimova J.Y., Fujita M., Lee B-S, Khazenzon N.M., Wachsmann-Hogiu S., Farkas D.L., Black K.L., Holler E., Cedars-Sinai Medical Center, US

Nanoconjugates of β-poly(L-malic acid) (PMLA) have been synthesized with modules active in drug delivery, drug release, blocking of tumor-affiliated mRNA by antisense oligonucleotides, penetration of blood and cellular barriers, tissue targeting, membrane permeation, fluorescence, and [...]

A Two-Dimensional Numerical Simulation of Organic Light-Emitting Devices

Li Y., Lee B-S, Lee J.W., Chen P., Chen W-H, Lee B-S, Lee J.W., Lu C-S, Chen P., Chen W-H, National Chiao Tung University, TW

Organic light-emitting devices (OLEDs) add a completely new dimension to current display technology [1-3]. OLED displays are thinner, lighter, brighter, and cheaper to manufacture; which also consume less power than the current thin displays do. [...]

A Novel SPICE Compatible Current Model for OLED Circuit Simulation

Li Y., Lee B-S, Lee J.W., Lee B-S, Lee J.W., Lu C-S, Chen W-H, National Chiao Tung University, TW

high quality, and low power consumption display [1-2]. It is known that the brightness of the OLED is controlled by the current density of the device; therefore, precisely controlling the current density of active matrix [...]