chitosan – Page 3 – TechConnect Briefs

Use of Nanoparticles as Therapy for Respiratory Syncytial Virus Inhibition

Vig K., Boyoglu S., Rangari V., Sun L., Singh A., Singh S.R., Pillai S., Singh A., Singh S.R., Alabama State University, US

Respiratory Syncytial Virus is the leading cause of severe respiratory illnesses such as bronchiolitis and pneumonia in young children. RSV is a paramyxovirus with negative-sense genomic RNA that encodes for eleven proteins, two of which, [...]

Efficient siRNA Delivery by Secondary and Tertiary Amine Modified Polysaccharides

Ghosn B., Singh A., Roy K., The University of Texas at Austin, US

As siRNA mediated therapy further develops, the need for biocompatible, effective delivery vectors, especially for mucosal delivery, is apparent. We report here a novel nanocarrier for siRNA delivery via targeted chemical modification of the polysaccharide [...]

Chitosan Nanoparticle Combined with Ultrasound for Cervical Cancer Detection

Tsai K-C, Shieh M.J., Yang S.J., Lin W-L, Chen W-S, Institute of Biomedical Engineering, TW

Photodynamic medicine is a novel approach for cancer detection and treatment via different photosensitizers and suitable light source. The 5-Aminolevulinic acid (5-ALA) can be converted into protoporphyrin IX (PpIX) that can be utilized as a [...]

Colorectal Cancer Cell Detection by Chitosan Nanoparticle Conjugated with Folic Acid

Yang S.J., Chen J-W, Shieh M.J., Institute of Biomedical Engineering, TW

Endoscopy is a common diagnosis device for the detection of colorectal cancer and there are two methods to improve the diagnostic sensitivity. One is chromoendoscopy, and the other is magnifying endoscopy. Color contrast dye, such [...]

Multifunctional Materials Based on Chitosan, Globular Protein and Gold Nanoparticles

Indrea E., Dreve S., Bratu I., Mihailescu G., Olenic L., Tomoaia G., Tomoaia-Cotisel M., Mocanu A., Horovitz O., Tomoaia-Cotisel M., Babes-Bolyai University of Cluj-Napoca, RO

Our studies are focused on the structure of thin films of chitosan and of globular protein in both the absence and the presence of negatively charged gold nanoparticles. Deacetilated chitosan of high molecular weight and [...]

Chitosan-Nanoparticle as UV Filter and Carrier for Cosmetic Actives

Wanichwecharungruang S.P., Assoc. Prof., TH

Chitosan derivative was prepared by grafting both phthaloyl groups and methoxy poly(ethylene glycol) moieties onto the polymer chain. Nanoparticles of the prepared chitosan derivative were then obtained through solvent displacement technique. The products are stable [...]

A Novel Detection of Early Colorectal Cancer by Chitosan Nanoparticles Conjugated with Folic Acid

Yang S.J., Lin F.H., Tsai K-C, Shieh M.J., Institute of Biomedical Engineering, National Taiwan University, TW

The 5-Aminolevulinic acid (5-ALA) can be converted into protoporphyrin IX (PpIX) that can be utilized as a fluorescent probe for tumor detection. In this study, folic acid was conjugated on chitosan molecules via covalent bond [...]

Fluorescent Nanoparticles Based on Chitosan

Bodnar M., Minko T., Hartmann J.F., Borbely J., University of Debrecen, HU

Chitosan is a basic linear polysaccharide containing β-[1→4]-linked 2-acetamido-2-deoxy-D-glucopyranose and 2-amino-2-deoxy-D-glucopyranose units. Because of the presence of reactive amino groups, chitosan can be modified easily to create nano- and micro particulate systems, films or porous [...]

Chitosan Nanoparticles for the Effective Vaccine Delivery System

Kim B.G., Kang I.J., Kyungwon University, KR

There are four genes of S, C, X, P in HV DNA. S gene has the pre-S region composed of pre-S1 and pre-S2 as an encoding gene of surface antigen. C gene is in the [...]

Application of nanoparticle in photodynamic diagnosis for colorectal cancer

Yang S.J., Peng C.L., Lai P.S., Lin F.H., Shieh M.J., National Taiwan University, TW

Photodynamic medicine is a novel approach for cancer therapy and diagonosis via different photosensitizers and suitable light source. The 5-Aminolevulinic acid (5-ALA) can be converted into protoporphyrin IX (Pp IX ) that can be utilized [...]