Chitosan derivative was prepared by grafting both phthaloyl groups and methoxy poly(ethylene glycol) moieties onto the polymer chain. Nanoparticles of the prepared chitosan derivative were then obtained through solvent displacement technique. The products are stable white particles with the average sizes of about 40-150 nm (dry particle) as shown by scanning electron microscopy (SEM) and transmission electron microscopy (TEM). Various cosmetic actives such as octyl methoxycinnamate, ascorbyl palmitate (vitamin C derivative) and astaxanthin could be successfully encapsulated into these chitosan-nanoparticles. UV screening property, antimicrobial activity and stability of the particles were investigated. Photostability of selected encapsulated cosmetic active was also compared to the un-encapsulated active.
Journal: TechConnect Briefs
Volume: 4, Technical Proceedings of the 2007 NSTI Nanotechnology Conference and Trade Show, Volume 4
Published: May 20, 2007
Pages: 257 - 260
Industry sector: Advanced Materials & Manufacturing
Topics: Nanoparticle Synthesis & Applications