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Taiwan

Cationic polystyrene nanosphere induces autophagy through inhibition of Akt/mTOR and activation of AMPK signaling pathways in macrophage and epithelial cells

Chiu H-W, Xia T., Tsai J-C, Chen C-W, Wang Y-J, National Cheng Kung University, Medical College, TW
Nanoparticles have been used to produce a wide range of products. Those include applications in imaging and drug delivery in medicine. However, the possible adverse biological effects in human being remain unclear. Autophagy is an [...]

A better biomaterial for bone regeneration: type II collagen

Tsai Y-H, Taipei Medical University, TW
Type II collagen facilitates osteogenesis and suppresses adipogenesis simultaneously during early stage of MSC differentiation, mediated through the same signaling cascades. Type II collagen-coated plates enhanced BMSC mineralization better than did either non-coated or type [...]

Study of protoporphyrin IX-loaded silica hollow spheres for Photodynamic therapy

Tseng G-H, Liu T.Y., National Yang-Ming University of Taiwan, TW
In this study, PpIX was loaded in the shell of silica hollow sphere with the expectation that PpIX-loaded silica hollow spheres (PpIX-SHS) might be employed as a PDT agent with ultrasound image contrast. The PpIX-loaded [...]

Study on the polymeric nanosphere with imaging functionality

Lin M-H, Liu T.Y., Institute of Biomedical Engineering, National Yang-Ming University, Taipei, 112 Taiwan (ROC), TW
The aim of this research was to develop a novel contrast agent with magnetic resonance (MR) imaging, fluorescent imaging and drug encapsulation functionalities. The zinc oxide (ZnO) nanoparticles and superparamagnetic iron oxide (Fe3O4) nanoparticleswas prepared [...]

Novel Photo-thermal Controlled Drug-releasing Vectors for Cancer Detection and Treatment

Tsai M-H, Ling D., Shieh M.J., National Taiwan University, TW
Cancer is always the leading cause of deaths in worldwide. The aim of this research is to develop a new generation of chemotherapeutic drugs with both photothermal activated drug release and MRI diagnostic function. Carbon [...]

Evaluation of F127 / chitosan hydrogel as a scaffold for bone repair

Yang M.-C., Lai W.-F., Taiwan University of Science & Technology/Taipei Medical University, TW
An in situ gelled scaffold for bone tissue engineering to restore the function of bone tissues is developed. The gel is comprised of Pluronic F127 and chitosan. The gelation temperature (Tgel), and viscoelastic properties and [...]

A Novel Near Infra-Red Fluorescent Probes to Repair Metal Artifact After Implantation

Chiu L-H, Kung F.-C., Yang M.-C., Tsai Y-H, Chang W.H., Lai W.-F.T., Taipei Medical University, Harvard Medical School/McLean Hospital, TW
Accurate, noninvasive techniques for monitoring bone-implant integration are demanded in clinic. Standard X-ray and CT provide a snapshot of the skeletal structure. However, metal artifact is an unsolved problem to visualize the CT image detail [...]

Synthesis and Characterization of Functionalized Magnetic Nanoparticles for Biomedical Applications

Wang L.F., Lo Y.L., Ke J.H., Kaohsiung Medical University, TW
One-pot synthesized polyacrylic acid-modified iron oxide (PAAIO) was decorated with a polymer, which was served as a reservoir for a therapeutic agent or a fluorescent dye via chemical or physical approaches. PAAIO possess specific magnetic [...]

Decomposition of Methanol Catalyzed by Cu-ZnO@C

Hong C.-I., Kang H.Y., Chang F-C, Paul Wang H., National Cheng Kung University, TW
Decomposition of methanol (DM) to CO and H2 can be catalyzed by Cu-ZnO@C core-shell nanoreactors. It is found that reactivity of DM catalyzed by the nanoreactors increase with an increase in the fractions of ZnO [...]

The Effects of Dwell_time of Monopolar Waveform on Droplet Formation through the Analysis of Fluid Propagation Direction

Wu C.H., Hwang W-S, National Cheng Kung University, TW
For inkjet printing, the fluid dynamics in a capillary tube caused by the movement of the piezoelectric material is essential due to the need to adjust the voltage pulse waveform, but it has seldom been [...]

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