Papers – Page 26 – TechConnect Briefs

Ultrastructural and mechanical effects of collagen cross-linking treatment on human corneo-scleral tissues

Choi S., Jung G.B., Cheong Y., Shin J.-H., Jin K.-H., Park H.K., Kyung Hee University, KR

The aim of this study was to quantitatively examine the immediate effects of a photooxidative collagen cross-linking treatment with photosensitizer riboflavin and 370 nm UVA light in in vitro rabbit dermal collagen fibrils. These effects [...]

Cardiomyocyte Function on Poly-Lactic-co-Glycolic Acid: Carbon Nanofiber Composites under Electrical Stimulation

Stout D.A., Webster T.J., Brown Univeristy, US

In recent research, it was demonstrated that the use of nano-materials can promote the growth of cardiomyocytes when compared to the use of conventional or micro-structured materials. One such nano-material consisted of poly-lactic-co-glycolic acid (PLGA) [...]

Smaller sizes of Ag-PVP Nanoparticles Control Inflammatory Responses, and Reduce CD80 and CD86 Expression Levels, in Macrophages Infected with Chlamydia trachomatis

Yilma A.N., Singh S.R., Dennis V.A., Alabama State University, US

Chlamydia trachomatis is an important cause of sexually transmitted infection that can manifest itself as either acute cervicitis, pelvic inflammatory disease, and more commonly as a chronic asymptomatic infection. Early intervention strategies that can reduce [...]

Targeted Cancer Therapy by Immunoconjugated Gold-Gold Sulfide Nanoparticles Using Protein-G as a Cofactor

Sun X.H., Zhang G.D., Patel D., Gobin A.M., University of Louisville, US

Gold-gold sulfide nanoparticle (GGS-NP) with controllable near infrared (nIR) absorption was synthesized from a simple reaction of chloroauric acid and sodium thiosulfate. Through PEGylated recombinant Protein-G (ProG), ProG-conjugated GGS-NPs for antibody capture by Fc domain [...]

Supermagnatic Iron Oxide Nanoparticles Toxicity to Mammalian Cells

Vig K., Tiwari P., Parveen A., Rangari V., Singh S.R., Alabama State University, US

The present study investigates the development of superparamagnetic iron oxide nanoparticles as a controlled release drug formulation and use as anticancer therapeutic agents. Iron oxide nanoparticles (IONPs) were synthesized using ultrasonic irradiation of iron pentacarbonyl [...]

Copper complexes loaded on nanostructured TiO2 materials as citotoxic agents of cancer cells

Lopez T., Guevara P., Gómez E., Instituto Nacional de Neurologia y Neurocirugia, MX

In the present work ammonium tetrachlorocuprate (II) and copper (II) chloride were loaded on nanostructured mesoporous titania for determinate their anticancer properties. Copper-TiO2 materials were prepared using the sol-gel technology. Characterization of Copper complexes and [...]

Mn-Zn Ferrite and Photosensitizer Co-Loaded Cancer Theranostic Agent for Magnetic Resonance Imaging and Photodynamic Therapy

Lai P.S., Lai S.M., Yang M.-D., Tung M.-J., Lai P.S., Lai S.M., National Chung Hsing University, TW

Developing a nanodevice with simultaneous cancer imaging and therapy is one of the promising approaches for cancer treatments. In this report, a multifunctional cancer theranostic system based on magnetic resonance (MR) contrast agent and photosensitizer [...]

Electrospun 5-fluorouracil loaded bovine serum albumin-polyvinylpyrrolidone nanofibers

Illangakoon U.E., Chatterton N.P., Williams G.R., Nazir T., London Metropolitan University, UK

5-FU loaded bovine serum albumin (BSA)/ polyvinylpyrrolidone (PVP) nanofibers prepared using an electrospinning process. The nanofibers were characterised by scanning electron microscopy (SEM) energy - dispersion spectroscopy (EDS), Fourier transform infrared spectroscopy (FTIR), X-ray diffraction [...]

VEGF-dependent mechanism of anti-angiogenic action of diamond nanoparticles in glioblastoma multiforme tumor

Grodzik M., Sawosz E., Wierzbicki M., Hotowy A., Prasek M., Jaworski S., Chwalibog A., Warsaw University of Life Sciences, PL

Inhibition of tumor angiogenesis suppresses tumor growth and prevents metastasis, and is a key target in cancer therapy. Novel materials, nanoparticles of carbon allotropes (C60 fullerenes, graphite nanoparticles, multi-walled carbon nanotubes, single-walled carbon nanotubes and [...]

Combined targeted hyperthermia and drug delivery with magnetic nanoparticles

Mitrelias T., Tselepi M., Barnes C., Orel V., Schepotin I., Cavendish NanoTherapeutics, UK

Cancer remains the second leading cause of deaths worldwide and in the U.S. alone every year there are over 1.5 million new diagnoses. Technologies that would allow targeted destruction of tumours by localising the delivery [...]