Papers – Page 32 – TechConnect Briefs

Highly robust array of nanosensing platform for biosensing application

Stateikina I., Ng A., Chinnappan R., Ahmed M., Zourob M., INRS, CA

This work presents a simple method of combining macro connectors with pre-fabricated nanovire chips. This design offers a unique ease and rapidity of connecting the nanowires with the connectors without using imaging and external aid [...]

From Rational Design to Probe Optimization: the Role of Nanoparticle Valency in Single Cancer Cell Detection in Blood via Magnetic Relaxation

Kaittanis C., Santra S., Perez J.M., University of Central Florida, US

The conjugation of targeting ligands to iron oxide nanoparticles has achieved the development of specific assays for the detection of biomedical targets through magnetic relaxation. However, limited studies investigated how the nanoparticle valency modulates the [...]

Identification of Molecular-Mimicry-Based Ligands for Cholera Diagnostics using Magnetic Relaxation

Santiesteban O.J., Kaittanis C., Banerjee T., Santra S., Teter K., Perez J.M., University of Central Florida, US

Magnetic nanosensors (MRnS) offer multiple benefits that can be used to design sensitive and robust diagnostic tools. High sensitivity, stability, and ease of surface modification make this approach a strong contender against the more commonly [...]

Portable gas sensor for breath analysis

Righettoni M., Tricoli A., Gass S., Pratsinis S.E., ETH Zürich, CH

The detection of acetone in the human breath is a promising method for the noninvasive diagnosis and monitoring of diabetes. Here, a portable and highly selective acetone-sensor was developed by direct flame synthesis and deposition [...]

A double-bead sandwich assay for protein detection in serum based on localized surface plasmon resonance

Jans H., Jans K., Jans H., Jans K., Stakenborg T., Borghs G., Maes G., Lagae L., IMEC, BE

In this study, the importance of pre-concentration is clearly demonstrated for the covalent immobilization of various proteins to magnetic nanoparticles through mild carbodiimide activation. Additionally, the covalently biofunctionalized magnetic nanoparticles are employed in a double-bead [...]

Topical Sensory Nanoparticles for in vivo Biomarker Detection

Patrone J., Benkoski J., Patchan M., Calderon-Colon X., Le H., Sample J., JHU/APL, US

We have recently developed a non-toxic, topically applied biosensor using solid lipid nanoparticles (SLN). This diagnostic platform is currently designed to continuously monitor hydrogen peroxide levels in skin. Overproduction of hydrogen peroxide is implicated in [...]

Drain Induced Barrier Lowering (DIBL) Effect on the Intrinsic Capacitances of Nano-Scale MOSFETs

Karim M.A., Venugopalan S., Chauhan Y.S., Lu D., Niknejad A., Hu C., University of California at Berkeley, US

MOSFET intrinsic capacitances going negative is a major concern in the compact model community. Negative Intrinsic Capacitances (NIC) can raise non-convergence issues in circuit simulators. In some cases NICs can be explained using physical phenomena. [...]

The Application of RESCUER Software to Modelling of Coupled Problems in Modern Devices

Zubert M., Napieralski A., Technical University of Lodz, PL

The simulation of modern electronic devices requiring taking into account physical phenomena of different nature such as electrical, mechanical, thermal or fluidic ones. The most of processes are governed by multidimensional partial differentialalgebraic equations (PDAEs). [...]

Hot-Carrier-Induced Current Degradation in Deep Sub-Micron MOSFETs from Subthreshold to Strong Inversion Region

Shihuan L., Nanyang Technology University, SG

In the past decades, as predicted by the Moore’s law, the IC circuit density increases to reduce the cost per chip and to achieve better performance. With critical device dimensions scaling down, the electrical field [...]

Analytical Solutions to Model the Line Edge Roughness and its Effect on Subthreshold Behavior of DG FinFETs

Monga U., Fjeldly T.A., Norwegian University of Science and Technology, and University Graduate Center (UNIK), NO

Statistical variability such as line edge roughness (LER) and random dopant effects have become major concerns in the nanoscale regime. Due to the intrinsic body, multigate devices such as FinFETs don’t suffer from random dopant [...]