Diagnostics & Bioimaging – Page 14

Fabrication of PEG Hydrogel Microstructures in Microfluidic System for Multicellular Spheroid Formation, Culturing and Analysis

Fu C.-Y., Chang H.-Y., National Tsing Hua University, TW

In this abstract, we describe a novel PEG-based, simple-to-fabricate, U-shaped micro-scale growth chamber, which allows cell trapping and forming into spheroids as well as culturing in the presence of a continuous perfusion flow, a long-term [...]

Investigation of optimal separation condition in negative dielectrophoresis force based particle sorting platform

Lee J-H., Kim B-K., Kim Y.H., Kim B-K., Kim Y.H., Kim B-K., Kim Y.H., Korea Aerospace University, KR

we investigate an optimal separation condition regarding the gravitation, the hydrodynamic force and the n-DEP force acting on particles in the sorting platform since contribution of each force is the main parameter to determine SE. [...]

Surface Plasmon Grating Coupled Emission from Organic Emitter for Detecting Refractive Index Variation

Chiu N.-F., Lee J-H., Lin C-W, National Taiwan Normal University, TW

We demonstrated the surface plasmon grating coupled emission (SPGCE) from photo-excited organic layer covered with metal thin film on the corrugated substrate. Directional emissions corresponded to the resonant condition of surface plasmon modes on the [...]

Experimental study of sensitivity enhancement in SPR biosensors by use of zinc oxide intermediary layers

Chiu N.-F., Singh A., Nelson-Fitzpatrick N., Dutt S., Evoy S., Lin C-W, National Taiwan Normal University, TW

We report a novel design for the intermediary layer of surface plasmon resonance (SPR) devices that use high refractive index and high-transmittance zinc oxide (ZnO) dielectric layers to enhance the signal quality and improve the [...]

Plasmonic nanostructure based biosensing

Patskovsky S., École Polytechnique de Montréal, CA

Plasmonics is quickly becoming a dominant technology in the fields of novel optical devices employing new experimental capabilities of subwavelength metallic nanostructures. In combination with modern nanofabrication technologies which allows preparation of numerous regular patterns [...]

Nano-plamsonics Sensing and Integration with Microfluidics for a Lab-on-chip Biosensor

Wei J.J., Rexius M., Kofke M., Wang Y., Singhal S., Waldeck D.H., CFD Research Corporation, US

Ordered arrays of nanostructures in metal films have been studied for practical miniaturization of SPR sensing and microfluidic integration. We report a nanostructure array that is designed to permit significantly enhanced Extraordinary Optical Transmission (EOT) [...]

High-throughput multiplex protein analysis for limited sample size on a single slide

Rozhok S., Ouyang K., Dixon D., Nelson M., NanoInk Inc, US

To meet the challenges of new genomic and proteomic applications, rapid and sensitive analysis of large numbers of interactions in parallel will be required. High-density microarrays are ideally suited for parallel multiplex screening of thousands [...]

Thin film-resistive gas sensor with SnO2/Au nanocomposite for hydrogen sulfide detection

Chang B-W, Ding S-J, Chen R.L.C., Hungkuang University, TW

A highly sensitive and selective H2S gas sensor has been developed by deposited a SnO2 thin film on an alumina substrate with a spin-coated method. This SnO2 sensing film was be made by a sol-gel [...]

Silica coated Magnetic Nanoparticles (SMNPs): Capture and Identification of Escherichia coli Cells using Surface Enhanced Raman Spectroscopy

Rastogi S.K., Jabal J., Zhang H., Haler K.J., Gibson C.M., Qiang Y., Aston D.E., Hurdlicka P.J., Branen A.L., University of Idaho, US

Silica coated Magnetic nanoparticles (SMNPs; SiO2/Fe3O4 + Fe2O3) were prepared by encapsulation of iron oxide NPs with silica dioxide using the sol-gel method and characterized through transmission and scanning electron microscopic imaging, magnetic hysteresis and [...]

Detecting Infectious Organisms: A Concerted Approach using Genomics, Molecular Engineering and Nano-enabled bio-MEMS Technologies

Keegan N., Spoors J., Flanagan K., Cockell S., Gendra E., Ko Ferrigno P., Hedley J., Wipat A., Harwood C., McNeil C.J., Newcastle University, UK

It is now widely accepted that a combination of nanotechnology and engineering that harnesses the full potential of genomic information through real-time predictive, preventive, point-of-care healthcare provision will lead to the next technological revolution. However, [...]