Biomaterials – Page 47 – TechConnect Briefs

Attenuated-Affinity Biotin Analogs for Catch-and-Release with Streptavidin

Corry S., Ying L-Q, Branchaud B., Life Technologies, US

The binding between streptavin and biotin, which is one of the strongest non-covalent interactions known in nature, is used ubiquitously in molecular biology. However, when a biotinylated molecule is captured for testing purposes and cannot [...]

Colloido-Polymersomes: Capsules consisting of a composite layer of particles and polymer

Shum H.C., University of Hong Kong, HK

We present an approach to fabricate capsules consisting of a composite layer of particles and block copolymers . The capsules are fabricated by the directed assembly of block copolymers at the interfaces of a double [...]

A Helical Peptide can Mediate Electron over 120 Å by Hopping Mechanism

Arikuma Y., Nakayama H., Morita T., Kimura S., Kyoto University, JP

We have studied long-range electron transfer through various lengths of helical peptides from 8 mer (24 Å) up to 80 mer (120 Å) in self-assembled monolayers prepared on a gold surface. Helical peptides carrying a [...]

Responsive Materials

Lo Presti C., Merck Serono, IT

Continuous advances in polymer chemistry are enabling the synthesis of novel responsive biomaterials. This class of biomaterials are polymers able to undergo significant changes in their properties in response to external stimuli. Depending on their [...]

Bio Nano Materials

Polyethylene-oxide (PEO) linear nano-polymer directly stimulates endothelium and protects myocardium from focal ischemia-reperfusion injury via eNOS pathway in rats

Uryash A., Arias J., Wu H., Adams J.A., Mount Sinai Medical Center, US

Medical grade Nano-polymers (NP) used to enhance circulation, drug and gene delivery. Injection of Polyethylene-oxide (PEO) increase tissue perfusion and decrease mean blood pressure in animal models. Polyethylene-oxide (PEO) NP’s ultra high molecular weight (2-5 [...]

Leveraging Ontologies for Improved Medical Outcomes Assessment: Implementing Medical Management Technology to Drive Innovation

Little E., CTG Life Sciences, US

Sensor data - such as that produced by many kinds of nanotechnologies - can be difficult to manage and maintain. This is especially true in areas of biomedicine where contextual information is important to capture [...]

Computational Modeling of Electromagnetically Induced Heating of Magnetic Nanoparticle Materials for Hyperthermic Cancer Treatment

Rast L., Harrison J.G., University of Alabama at Birmingham, US

We present results on the computational modeling of electromagnetically induced heating for the purpose of hyperthermic cancer treatment with magnetic nanoparticle fluids. Magnetic hyperthermia can therefore be used for direct targeting and destruction of tumors [...]

Determination of the Electroporation Threshold for pulses from 95 ns to 20 us

Saulis G., Balevicius S., Saule R., Stankevic V., Zurauskiene N., Vytautas Magnus University, LT

The dependences of the fraction of electroporated mouse hepatoma MH-22A cells on the pulse intensity were obtained for the cells exposed to single square-wave electric pulses with the durations from 95 ns to 20 us. [...]

Analysis of the Relationships Between the Parameters of the Electric Pulse

Saulis G., Vytautas Magnus University, LT

Theoretical relationships between the parameters of the electric pulse which is necessary for the poration of the cell have been obtained. Analysis has been made for the square wave, exponential and sine wave ac electric [...]