Biomaterials – Page 101 – TechConnect Briefs

A Novel Class of Sensors for System Integrative Concepts in Biotechnological Applications

Schober A., Kittler G., Kittler M., Buchheim C., Majdeddin A., Cimalla V., Fischer M., Yanev V., Himmerlich M., Krischok S., Schaefer J.A., Romanus H., Sändig T., Burgold J., Weise F., Wurmus H., Drüe K.H., Hintz M., Thust H., Gebinoga M., Kittler G., Kittler M., Spitznas A., Gottwald E., Weibezahn K-F., Wegener D., Schwienhorst A., Ambacher O., Technical University of Ilmenau, DE

The application of an system integrative approach based on hetereostructure sensors (group III nitrides) for the examination of differnt biological systems is shown and discussed.

Controlling Colorimetric Reversibility of Nanostructured Polydiacetylenes

Lee C.H., Lee J.S., Lee C.H., Lee J.S., Park H-W., Lee C.H., Lee J.S., Ahn D.J., Kim J-M, Hanyang University, KR

Polydiacetylene liposome has specific color change of blue to red upon various kinds of stimuli. Stimuli can be a antigen-antybody, thermal stimuli and Ph change and even physical contact. From these charecteristics polydiacetylene used a [...]

Electrical Detection of DNA Hybridization using Adjacent Impedance Probing (AIP) Method

Zhou H., Ma K-S, Madou M., Zoval J., Madou M., University of California Irvine, US

Sensitivity and selectivity are two of the most challenging criteria for the development of DNA biosensor devices. These biosensor devices have attracted interest for the rapid identification of pathogens in humans, animals, and plants, for [...]

A Piezoelectric Micro-Cantilever Bio-Sensor Using the Mass-Micro-Balancing Technique with Self-Excitation

Lee Y., Lim G., Moon W., Pohang University of Science and Technology, KR

A new bio-sensor was developed in order to use in a LOC(Lab-On-a-Chip). The sensor detects the change in the resonance frequency of a micro cantilever with a piezoelectric film(PZT). This is the so-called mass micro-balancing [...]

Detecting Drug Screen by Acoustic Wave Sensor

Shih C-J, Ke W-W, Lieu C-H, ITRI, TW

The Severe Acute Respiratory Syndrome (SARS) is induced to the patients pervasively pneumonia and respired exhaustion. In previously study (2), the nucleic acid 318 and 510 of S protein was the crucial fragments to bind [...]

Label Free Colorimetric Detection of Single Nucleotide Polymorphisms in Pcr Amplified Genomic DNA

Li H.X., Rothberg L.J., University of Rochester, US

Analysis of DNA is increasingly important in clinical diagnosis, pathology and genetics1, 2. Single nucleotide polymorphisms (SNPs) in genomic DNA are known to be responsible for a number of hereditary conditions3 and cancers4. Nearly all [...]

Rapid DNA Sequence Identification based on Electrostatic Interactions with Unmodified Gold Nanoparticles

Li H.X., Rothberg L.J., University of Rochester, US

Sequence-specific detection of DNA play more and more important role in clinical diagnosis and molecular biology research. Most assays identify specific sequence through hybridization of an immobilized probe to the target analyte after the latter [...]

Microchannel Immunoassays with Electrochemical Detection in Devices Constructed from Low Temperature Co-fired Ceramic and Screen Printed Gold

Fakunle E.S.O., Fritsch I., University of Arkansas, US

We report the first self-contained electrochemical enzyme linked immunosorbent assay in microchannel devices constructed from low temperature co-fired ceramic (LTCC) with screen-printed gold for fast and sensitive assays. No one has previously reported a device [...]

CNTs-Insulator- Semiconductor System for Chemical and Biological Sensor Applications

Cheon J-H, Lin Q., Kong B-D, Kang D.W., Kim L., Suh J.S., Park Y.J., Min H.S., Seoul National University, KR

In this paper, an Electrolyte-CNTs-Insulator-Semiconductor capacitor has been prepared due to compatibility with CMOS technology. To prepare this capacitor, we used the bonding technique to combine the MWNT array.It shows that the surface potential modulation [...]

Utilizing Nanoscale Patterned Proteins to Create Neuronal Cells Circuits

Wang W., Chun C-J, Gregory C., Narayanan S., Poeta M., Hickman J.J., University of Centra Florida, US

Micro-patterning of neuronal cells in vitro is a critical step for studies in the fundamental biology of neuron-neuron and neuron-surface interactions. The culturing of the neuronal cells on patterned self-assembled monolayers (SAMs), in some cases, [...]