Sector: Medical & Biotech
Cytotoxic studies of PEG functionalized ZnO Nanoparticles on MCF-7 cancer cells
Rodriguez Martinez C., Ramirez Vick J.E., Perales O., Singh S.P., University of Puerto Rico-Mayagüez, US
Nanoparticles have shown great promise in biomedical applications. Zinc oxide (ZnO) nanoparticles are being explored for various applications such as sun screen lotion, antimicrobial properties, advanced textiles, photodynamic therapy and electronic devices. We have synthesized [...]
Sulfur-33 Nanoparticles: A Possible Target for Neutron Capture Therapy of Cancer
Sulfur nanoparticles, enriched in the isotope S-33 are potential neutron capturers for enhancing neutron radiation dose in tumors, because of a nuclear reaction of this isotope which produces a high energy alpha particle which delivers [...]
In-vitro testing of realgar nanoparticles for treatment of multiple myeloma cells
Balaz P., Sedlak J., Pastorek M., Cholujova D., Bujnakova Z., Institute of Geotechnics, Slovak Academy of Sciences, SK
Realgar As4S4 has been used in traditional Chinese medicine externally or even orally to treat psoriasis,syphilis and malaria.However,its broader healing effect was documented recently.The possibility to synthesize realgar particles as nanosuspensions brings new therapeutic strategies [...]
Investigation of Taxol effects on morphological and micromechanical properties of human endometrial adenocarcinoma cells by AFM
Kim J.H., Kim K.S., Cho C.H., Choi Y.J., Kim J.H., Kim K.S., Choi Y.J., Jung G.B., Jung M-H, Yoon K-S, Woo Lee J., Lee G.J., Jung G.B., Jung M-H, Park H.K., Kyung Hee University, KR
The effects of Taxol on morphological and micromechanical properties of human endometrial adenocarcinoma (Ishikawa cell), were investigated by atomic force microscopy (AFM). The morphological and mechanical properties of the Ishikawa cell were significantly changed by [...]
Folate-Conjugated Gold Nanoparticles for Cancer Nanotechnology Applications
A need exists to target cancer treatments specifically to the tumor site, without damaging healthy tissue. This need can be achieved through the proper application of nanotechnology, namely gold nanoparticles conjugated to Folate. Folate is [...]
Importance of Solid Lipid Nanoparticles in Cancer Therapy
A drug delivery system can be defined as a system that capable of releasing a carried bioactive agents in a specific location within the body at a specific rate. Anti- cancer drugs can be associated [...]
Effects of Caffeic Acid Incorporated into Solid Lipid Nanoparticles in Cancer Cells
Nanotechnology has great potential to make an important role in prevention of cancer, detection, diagnosis, imaging and treatment. Nanoparticles are at the cutting edge of the rapidly developing area of nanotechnology. Solid lipid nanoparticles (SLNs) [...]
Overcome the Doxorubicin Resistance by Multimodal Nanoparticles in Mice
The efficacy of many chemotherapeutic agents is reduced in cells that have developed multiple drug resistance (MDR). To address this important problem, a biodegradable polymer was coupled to the photosensitizer and the resulting photosensitizer-nanoparticles were [...]
The Effect of Anticancer Nanotherapy on Lewis Lung Carcinoma
Orel V.E., Shevchenko A.D., Nikolov N.A., Dzyatkovskya N.N., Romanov A.V., Richalskiy A.Yu., Burlaka A.P., Lukin S.M., Uvarov V.N., Schepotin I.B., National Cancer Institute, UA
Introduction. Current forms of antitumor anthracycline antibiotic doxorubicin (DOXO) are highly toxic to the patient and can cause systematic complications, most notably cardiotoxicity. Systemic toxicity can seriously decrease the effectiveness of the drug since a [...]