Sector: Medical & Biotech
Ceria Nanopartciles Reduce Disease Severity in a Mouse Model of Multiple Sclerosis
Multiple sclerosis affects 300,00 people in the United States alone with 400 additional cases diagnosed each week. The first phase of the disease , is a relapse-remitting period where the patients symptoms wax and wane [...]
Molecular Changes in Rat Brain Due to Air Nano Pollution
Ljubimova J.Y., Gangalum P.R., Portilla-Arias J., Patil R., Konda B., Paff M., Markman J., Inoue S., Espinoza A., Chesnokova A., Kleinman M., Holler E., Black K.L., Cedars-Sinai Medical Center, US
Air pollution has been found to cause neurodegeneration, deposition of heavy metals & beta amyloid plaques in the brain. Air pollution constitutes of nanopollutant of different sizes that can enter the system and cause diseases. [...]
Ultrastructure of hepatic cells in rabbits after injection of nanoparticles MCS-B
In order to determine ultrastructural reconstructions in hepatic cells under effect of nanoparticles of magnetite (MCS-B), an experiment was conducted on 45 rabbits. Ultrastructural changes in hepatocyte organelles manifested pronounced signs of activation of reparative [...]
Functionalized Self-Assembling Peptides for Immediate Hemostasis and Accelerative Liver Tissue Regeneration
Cheng T.Y., Wu H.C., Chang W.H., Huang M.Y., Lee C.H., Wang T.-W., Department of Materials Science and Engineering, National Tsing Hua University, TW
Traumatic injury or surgery may trigger extensive bleeding. However, conventional hemostatic methods have limited efficacy and may cause surrounding tissue damage. In this study, we use self-assembling peptides (SAPs) and specifically extend fragments of functional [...]
Ultrastructural and mechanical effects of collagen cross-linking treatment on human corneo-scleral tissues
The aim of this study was to quantitatively examine the immediate effects of a photooxidative collagen cross-linking treatment with photosensitizer riboflavin and 370 nm UVA light in in vitro rabbit dermal collagen fibrils. These effects [...]
Cardiomyocyte Function on Poly-Lactic-co-Glycolic Acid: Carbon Nanofiber Composites under Electrical Stimulation
In recent research, it was demonstrated that the use of nano-materials can promote the growth of cardiomyocytes when compared to the use of conventional or micro-structured materials. One such nano-material consisted of poly-lactic-co-glycolic acid (PLGA) [...]
Smaller sizes of Ag-PVP Nanoparticles Control Inflammatory Responses, and Reduce CD80 and CD86 Expression Levels, in Macrophages Infected with Chlamydia trachomatis
Chlamydia trachomatis is an important cause of sexually transmitted infection that can manifest itself as either acute cervicitis, pelvic inflammatory disease, and more commonly as a chronic asymptomatic infection. Early intervention strategies that can reduce [...]
Targeted Cancer Therapy by Immunoconjugated Gold-Gold Sulfide Nanoparticles Using Protein-G as a Cofactor
Gold-gold sulfide nanoparticle (GGS-NP) with controllable near infrared (nIR) absorption was synthesized from a simple reaction of chloroauric acid and sodium thiosulfate. Through PEGylated recombinant Protein-G (ProG), ProG-conjugated GGS-NPs for antibody capture by Fc domain [...]
Supermagnatic Iron Oxide Nanoparticles Toxicity to Mammalian Cells
The present study investigates the development of superparamagnetic iron oxide nanoparticles as a controlled release drug formulation and use as anticancer therapeutic agents. Iron oxide nanoparticles (IONPs) were synthesized using ultrasonic irradiation of iron pentacarbonyl [...]