Medical & Biotech – Page 19 – TechConnect Briefs

In vitro reduction of mycotoxins and other inflammatory mediators from whole blood using CytoSorb® hemoadsorbent polymer beads

Scheirer A.R., Rueggeberg K.-G., Golobish T.D., Guliashvili T., Gruda M.C., O’Sullivan P., Chan P.P., CytoSorbents Corporation, US

Opportunistic fungal infections account for up to 25% of all hospital-acquired blood infections. Patients at highest risk are those with weakened immune systems, and include elderly patients, patients with cancer or HIV infection, and patients [...]

Comparing Biocompatibility of Titanium Orthopaedic Implants With and Without an Ultra-thin Coating of TiO2 by Ion Beam Assisted Deposition

Miralami R., Namavar F., Thiele G.M., Sharp J.G., Garvin K.L., University of Nebraska Medical Center, US

Introduction: Annually, more than one million Americans undergo arthroplastic surgeries, and by 2030 the projected number will exceed more than four million [1]. Thus, there is a serious need to accommodate such overload. It has [...]

A synergistic approach to the design, fabrication and evaluation of 3D printed micro and nano featured scaffolds for vascularized bone tissue repair

Holmes B., Bulusu K., Plesniak M., Zhang L.G., Nanochon LLC, George Washington University, US

In recent years, 3D printing has become a popular and widely investigated method for the fabrication of large bone implants. 3D printed bone constructs, devices and treatments hold great potential to repair traumatic and chronic [...]

Stable Magnetic Isotopes as New Trend in Nanonuclear Biotechnology

Koltover V., Institute of Problems of Chemical Physics, Russian Academy of Sciences, RU

With dimensions of the order of tens angstroms, biomolecular devices are assigned, in modern terminology, to objects of “nanophysics”. At the same time, all of them are composed from chemical elements many of which have [...]

Strategies for production of naturally-derived calcium phosphates particles for solid free-form fabrication

Miculescu F., Miculescu M., Maidaniuc A., Voicu S.I., Miculescu F., Miculescu M., Batalu D., University Politehnica from Bucharest, RO

In this abstract we propose the strategies optimization for obtaining ceramic materials derived from natural sources for solid free-form fabrication, used for bone substitution. The selected method, thermal processing, is simple (due to the similarities [...]

Biofilm as a versatile stablizer and promoter for Pd nanoparticle (PdNP) recovery and catalytic denitrification

Zhou C., Rittmann B.E., Wang Z., Ontiveros-Valencia A., Krajmalnik-Brown R., Arizona State University, US

There is an increasing demand on recycling of palladium from mining waste streams for purposes of resource retrieval and catalytic application. We introduced the novel H2-based membrane biofilm reactor (MBfR) technology to recover Pd in [...]

Biomaterials

Dex40-GTMAC3, modified dextran as a novel heparin antagonist

Kalaska B., Kaminski K., Sokolowska E., Czaplicki D., Kujdowicz M., Stalinska K., Szczubialka K., Bereta J., Pawlak D., Nowakowska M., Mogielnicki A., Medical University of Bialystok, PL

Protamine is the only registered antidote preventing bleeding of patients treated with unfractionated heparin (UFH). However protamine may induce anaphylactic shock or serious hypotension. We aimed to develop an alternative fully synthetic UFH antidote as [...]

Nonclinical evaluation of heparin binding copolymer – HBC1 for restoring of blood coagulation after heparin treatment

Kalaska B., Sokolowska E., Kaminski K., Miklosz J., Shin-ichi Y., Błazejczyk A., Wietrzyk J., Kasacka I., Szczubialka K., Pawlak D., Nowakowska M., Mogielnicki A., Medical University of Bialystok, PL

The incredible progress and wide use of various medical devices during intravascular or cardiac interventions increased the need for administration of anticoagulants, such as heparins. Protamine sulfate – a protein isolated from salmons is the [...]

Electrophoretic Coating of Hydroxyapatite-Boron Nitride Nanocomposites on Titanium Implants

Bakan F., Sezen M., Goncu Y., Ay N., Sabanci University, TR

Titanium (Ti) and its alloys have long been used as implant materials in dental and orthopedic applications. However, they can suffer certain disadvantages, such as poor osteoinductive properties and low corrosive-wear resistance. The potential of [...]