Medical & Biotech – Page 143 – TechConnect Briefs

Applications of Dielectrophoretic / electrohydrodynamic electrodes for concentration of biological nanoparticles

Fatoyino H.O., Huebner Y., Hoettges K.F., Hughes M.P., Labeed F.H., University of Surrey, UK

Dielectrophoresis (DEP) is a phemomenon of induced particle motion in non-uniform electric fields. The effect is frequency dependent; by monitoring the motion of particles in AC fields and ananlysing the change in motion with frequency, [...]

Nanoengineered Encapsulation of Organic Microcrystal as Novel Biolabels

Mak W.C., Cheung K.Y., Renneberg R., Trau D., National University of Singapore, SG

Here we report on our latest developments for nanoengineered encapsulation and surface design of micro and submicron crystals for biochemcial assay. Improvement has been made by decreasing the size of the organic crystals to submicrometer [...]

Biomolecular diagnostics by a magnetic lab-on-a-chip

Brückl H., Eggeling M., Heer R., Nöhammer C., Schotter J., ARC Seibersdorf Research GmbH, AT

Compared to the established fluorescent labeling method, the use of magnetic markers in biochip sensors has important advantages with respect to the detection of biomolecules at low concentrations. Additionally, the direct availability of an electronic [...]

A Sensitive Peptide-Nanotube Based Pathogen Assay

MacCuspie R.I., Banerjee I.A., Gummalla S., Mostowski H., Krause P., Matsui H., Hunter College, US

A novel peptide nanotube-based multiplexed pathogen assay has been developed that has high sensitivity, detecting as few as 100 pathogens per mL in as little as 0.5mL. Multifunctional nanotubes detect viruses by selectively binding antibody [...]

Direct-Write CMOS-Based Laboratory-On-Chip

Ghafar-Zadeh E., Sawan M., Therriault D., École Polytechnique de Montréal, CA

Over the recent years, the identification of genes which influence many diseases has been highly demanded and now, molecular diagnosis is most promising technology to offer fast and early detection of diseases to a maximum [...]

Magnetic Devices for Ultra High Throughput Biological Analysis

Mitrelias T., Jiang Z., Llandro J., Bland J.A.C., University of Cambridge, UK

In this report we present an integrated microfluidic cell for detecting and sorting magnetic beads in solution. The cell has been developed for magnetic biosensing, which comprises both magnetoresistive sensors optimized for the detection of [...]

Biosensors Fabricated through Electrostatic Assembly of Enzymes/Polyelectrolyte Hybrid Layers on Carbon Nanotubes

Lin Y., Liu G., Wang J., Pacific Northwest National laboratory, US

Carbon nanotubes (CNTs) have emerged as a new class of nanomaterials that is receiving considerable interest because of their unique structure and mechanical and electronic properties. One promising application of CNTs involves their use in [...]

Carbon Microstructures for Glucose Biosensor

Xu H., Malladi K., Wang C., Madou M.J., University of California Irvine, US

In this work we report on a novel design and fabrication of glucose sensor based on carbon post electrode array. Apart from the fact that carbon has a wide electrochemical stability window, one advantage of [...]

Surface modification and characterization of a cyclic olefin copolymer for magnetic bead-based stop-flow microfluidic ELISA

Herrmann M., Veres T., Tabrizian M., McGill University, CA

This abstract describes a microfluidic platform for simple, highly effective and parallel Enzyme Linked Immuno-Sorbent Assay (ELISA). The method is based on the use of magnetic micro-beads in order to increase the capture rate of [...]

Assembly of DNA Rotaxanes for AFM Based DNA Sequencing

Spadola Q., Qamar S., Lin L., Lindsay S.M., Ashcroft B., Zhang P., Lindsay S.M., The Biodesign Institute at Arizona State University, US

The desire to sequence DNA is fueled by the knowledge that the information locked inside of genomes can help fields as varied as molecular medicine, bioarcheology, forensics, and environmental science. The challenge is to establish [...]