Medical & Biotech – Page 142 – TechConnect Briefs

Molecular Dynamics Simulation of a Single Stranded (ss) DNA

Chatterjee S., Gersten B., Thakur S., Burin A., Queens College, CUNY, US

The objective of this study was to develop an understanding of the essential physical properties of short-single stranded DNA (ssDNA) towards the development of new DNA based biosensors. To achieve this goal, various thermodynamic properties [...]

Modeling of Cellular Communication

Barjis I., Barjis J., Samarrai W., Augustin I., Barjis I., Barjis J., New York City College of Technology, US

This paper introduces application of Rule based to molecular biology. In particular, it illustrates how by means of rule based the process of cellular communication can be modeled, and analyzed, where the model could be [...]

Computational Modeling in Life Sciences

Reflex-arc on a chip: An in silico cell culture analogue

Wilson K.A., Das M., Molnar P., Hickman J.J., University of Central Florida, US

To overcome the shortcomings of in vitro and animal models we are developing a microscopic cell culture analogue (microCCA) of the spinal reflex-arc. The present work draws on advances in a wide variety of technical [...]

Preservation of DNA and Protein Biofunctionality for Bio-MEMS & NEMS Fabrication

Trau D., Jie J., Sucher N.J., National University of Singapore (NUS), SG

Microfabrication processes especially in silicon are not compatible with biomolecules. For example, silicon processing is commonly performed at high temperatures and makes use of aggressive chemicals. Under these conditions biological materials are denaturated or decomposed. [...]

Design of a Wireless Passive Microsensor for Injection into the Human Brain

Spratley J.P.F., Hall P.S., Ward M.C.L., University of Birmingham, UK

The design of a sensor for injection into the human brain to aid sufferers of spinal injuries and neurological dissorders is outlined. It is powered and communicates by induction from an external coil, and incorporates [...]

Remote Manipulation of a Robotic Arm by Using Infrared Sensors

Chávez Rodríguez N.E., Esquivel Villar J., UNAM, MX

This project consists in adapting a remote operation system for a robotic arm by using infrared sensors to control its movements. A personal com-puter was used to send instructions to the robotic arm, instead of [...]

Stem Cell Differentiation Base on Acoustic Wave Sensor

Shih C-J, Tsai B-C, Ou K-L, Industrial Technology Research Institute, TW

This project was based on immobilizing bio-material. We used a new application for protein array and studied a new acoustic wave sensor which is based on silicon. We used the MEMS fabrication and the property [...]

Ligand-dependent changes in the SPR of magnetic nanoparticles

Radu L., Caruntu D., White M., Wiley J., Hanson P., University of New Orleans, US

Currently, there is an increasing interest in using magnetite nanoparticles in biological and medical applications. The interest is driven by a combination of their biocompatibility, chemical stability and magnetic properties. Magnetite nanoparticles with diameter 10 [...]

Fast and Easy Detection System of Protein Glycosylation by Using Resonant Energy Transfer between Nanoparticles

Oh E., Lee D., Kim H-S, Korea Advanced Institute of Science and Technology, KR

We construct the new glycosylation detection system using Resonance Energy Transfer (RET) between gold nanoparticles (AuNPs) and semiconductor quantum dots (QDs). RET can be induced by biomolecular interactions between concanavalin A (conA)-conjugated AuNP (conA-AuNP) as [...]