MacCuspie R.I. – TechConnect Briefs

A Framework for Identifying Sustainability Performance Targets for Nanomaterials

MacCuspie R.I., Micher L., Nance J., Watkins J., Hyman H., Srinivasan S., Dhau J., Yakymyshyn C., Drake C., Florida Polytechnic University, US

A current challenge facing the application of nano-enabled products is how to evaluate sustainable solutions and develop performance criteria? This work describes the application of an Input-Process-Output (IPO) model as a framework for a life-cycle [...]

Potential artifacts when evaluating the ecotoxicological effects of nanomaterials

Petersen E.J., Henry T.B., Zhao J., MacCuspie R.I., Kirschling T.L., Xing B., Dobrovolskaia M.A., Hackley V., White J.C., National Institute of Standards and Technology, US

Novel physicochemistries of engineered nanomaterials (ENMs) offer considerable commercial potential for new products and processes, but also the possibility of unforeseen and negative consequences upon ENM release into the environment. Investigations of ENM ecotoxicity have [...]

Potential artifacts when evaluating the ecotoxicological effects of nanomaterials

Petersen E.J., Henry T.B., Zhao J., MacCuspie R.I., Kirschling T.L., Xing B., Dobrovolskaia M.A., Hackley V., White J.C., National Institute of Standards and Technology, US

Novel physicochemistries of engineered nanomaterials (ENMs) offer considerable commercial potential for new products and processes, but also the possibility of unforeseen and negative consequences upon ENM release into the environment. Investigations of ENM ecotoxicity have [...]

Use of Single Particle Inductively Coupled Plasma Mass Spectrometry to Characterize a New Silver Nanoparticle Reference Material

Murphy K.E., Liu J., Guthrie W.F., Gorham J.M., Bonevich J.E., Allen A.J., Winchester M.R., Hackley V.A., MacCuspie R.I., National Institute of Standards and Technology, US

In this study we use a conventional inductively coupled plasma mass spectrometer operated in single particle mode (spICP-MS) to simultaneously characterize the size distribution and dissolved silver fraction of a new candidate silver nanoparticle reference [...]

“Just Add Water” – “Instant” singly-dispersed suspensions of silver nanoparticles on demand

MacCuspie R.I., National Institute of Standards and Technology, US

The rapid pace of development of new nanomaterials and new applications has also attracted much attention from the environmental health and safety (EHS) risk assessment community. Subsequently, calls for well-characterized common test materials from a [...]

Optimizing Instrument Operation and Data Processing for Single Particle Inductively Coupled Plasma Mass Spectrometry Measurement of Gold Nanoparticles

Liu J., Murphy K.E., MacCuspie R.I., Winchester M.R., National Institute of Standards and Technology, US

In recent years, inductively coupled plasma mass spectrometry (ICP-MS) operated in time-resolved analysis (TRA) mode has merged as a promising analytical tool capable of both sizing and counting metal containing nanoparticles in aqueous suspensions. In [...]

Synthesis of Janus Nanorods for Assemblies of Thermoresponsive Rod Pairs

MacCuspie R.I., Park K., Naik R., Vaia R.A., Air Force Research Lab, US

Janus particles offer unique functionality; for example micron-scale Janus spheres are used for electronic paper. At the nanoscale, reproducible, scalable fabrication of Janus particles is one of the key enabling technologies for “bottom-up” assembly processes. [...]

A Sensitive Peptide-Nanotube Based Pathogen Assay

MacCuspie R.I., Banerjee I.A., Gummalla S., Mostowski H., Krause P., Matsui H., Hunter College, US

A novel peptide nanotube-based multiplexed pathogen assay has been developed that has high sensitivity, detecting as few as 100 pathogens per mL in as little as 0.5mL. Multifunctional nanotubes detect viruses by selectively binding antibody [...]