hyperthermia – TechConnect Briefs

Overcoming Challenges in Manufacturing Scale-Up of Plasmonic Gold Nanorods: Bringing Photothermal Therapy to the Clinic.

Pagliaro L., Siva Therapeutics Inc, US

Siva Therapeutics is developing a simple, safe, and effective adjunct cancer treatment termed Targeted Hyperthermia™, which generates therapeutic heat emanating from within solid tumors using systemically injected precision gold nanorods and an infrared light engine [...]

Optimization of synthesis conditions to prepare desired shell thickness of superparamagnetic MgFe2O4@SiO2 core-shell nanosphere for biomedical applications

Das H., Debnath N., Arai T., Sakamoto N., Shinozaki K., Suzuki H., Wakiya N., Shizuoka University, JP

We have described here a simple way for the fabrication of superparamagnetic MgFe2O4@SiO2 core-shell spherical nanoparticles with controlled shell thickness. First, core MgFe2O4 dense nano-spheres were directly synthesized by ultrasonic spray pyrolysis (USP) technique from [...]

Magnetic Nanoparticles for Radio Frequency Hyperthermia: Preparation and Surface Functionalization Effects on Cellular Uptake

Gilliland III S.E., Carpenter E.E., Shultz M.D., McGuire VA Medical Center, US

Iron oxide nanoparticles have received sustained interest for biomedical applications as synthetic approaches are continually developed for precise control of nanoparticle properties. This work presents an investigation of parameters in the benzyl alcohol synthesis of [...]

Enhanced Cell Electro-permeabilisation Combined with Phototherapy to Target-Killing Cancer Cells by Using Multi Functional Carbon Nanotubes

Lee P-C, National Taiwan University, TW

Carbon nanotubes (CNTs) have been proposed and actively explored as multifunctional innovative carriers for drug delivery. This project presents a new modality for cell electro-permeabilisation based on the use of CNTs and external static electric [...]

Computational Modeling of Electromagnetically Induced Heating of Magnetic Nanoparticle Materials for Hyperthermic Cancer Treatment

Rast L., Harrison J.G., University of Alabama at Birmingham, US

We present results on the computational modeling of electromagnetically induced heating for the purpose of hyperthermic cancer treatment with magnetic nanoparticle fluids. Magnetic hyperthermia can therefore be used for direct targeting and destruction of tumors [...]

Development of new thermo-ablation therapy using magnetic nanoparticles and device for alternating magnetic field

Hashimoto S., Oda T., Yamada K., Ohara Y., Ohkohchi N., Kanamori T., Ikehata Y., Nagano I., Yanagihara H., Kishimoto M., Kita E., University of Tsukuba, JP

Although induction heating cancer therapy (IHCT) using magnetic nanoparticles can be a promising approach to treatment-less multi-nodular cancers, combination of conventional super paramagnetic particle (SPIO) and standard alternating magnetic field (AMF) generator confer insufficient heat [...]

Evaluation of Tools for Nanoparticles-modulated Hyperthermia by Atomic Force Microscopy

Reshetov I.V., Chissov V.I., Sukharev S.S., Matorin O.V., Korizky A.V., P.A.Hertzen Moscow Research Oncological Institute (MROI), RU

Some of the properties of the medicinal forms and tools, supposed to be used as hyperthermia modulators, can be evaluated by the atomic force microscopy (AFM): sizes and concentration of nanoparticles, their capability for the [...]

Thermoresponsive Magnetic Micelles for Simultaneous Magnetic Hyperthermia and Drug Delivery

Kim D-H., Elena R., Rajh T., Bader S.D., Novosad V., Argonne National Laboratory, US

Hyperthermia has been shown to be a potentially effective therapeutic modality in cancer treatment as it intensifies the efficacy of chemotherapy. The hyperthermia has a good synergic effect with chemotherapy. Their sensitivity to chemotherapy after [...]

Functionalized Inorganic Nanostructures for Biomedical Applications

Bonroy K., Jans H., Jans K., Van de Broek B., Van Meerbergen B., Van Summeren A., Jans H., Jans K., Reekmans G., Van de Broek B., Van Meerbergen B., Van Summeren A., Van de Broek B., Van Meerbergen B., Van Summeren A., Huang C., Stakenborg T., Trekker J., Willems M., Bartic C., Verhaegen K., Borghs G., IMEC, BE

Nanomaterials differ significantly from other materials due to two factors: increased surface area and quantumsize effects. These factors can enhance properties such as reactivity, strength and physical characteristics. Due to these characteristics, the coupling of [...]

Bacterial Drug Delivery Systems and nanoparticles

Sharma R., Haik Y., UNCG, US