Fluorescence – Page 3 – TechConnect Briefs

Optical chemical sensors on the base of arrays of ink-jet printed micro- and nanoparticles

Alfimov M.V., Sazhnikov V.A., Khlebunov A.A., Ionov D.S., Petrov A.N., Aristarkhov V.M., Men’shikova A.Y., Shevchenko N.N., Yakimansky A.V., Kalinin D.V., Plekhanov A.I., Photochemistry Center of RAS, RU

Array-based optical chemical sensors is a topic of growing interest for researchers. The main advantage of such systems is the possibility of optimizing the performance of sensor array by means of “tuning” individual sensor elements. [...]

Upconverting nanoparticles for in vitro and in vivo cellular imaging

Chatterjee D.K., Zhang Y., National University of Singapore, SG

Conventional fluorescent labels are of limited in vivo utility because short-wavelength radiation penetrates tissues poorly and excites strong background autofluorescence. Upconversion nanoparticles (UCN) convert low-energy exciting photons to visible emissions, resulting in deep tissue penetration [...]

Biomolecular activity switch: an application of metallic nanoparticle plasmon resonance

Alper J., Wijaya A., Crespo M., DeFlores L., Tokmakoff A., Hamad-Schifferli K., Massachusetts Institute of Technology, US

Specific external control of biomolecular activity is a critical step in harnessing the power of nature’s molecular machinery. We propose and demonstrate one control method, a biomolecular activity switch. Since proteins are the primary macromolecule [...]

The real-time, simultaneous analysis of nanoparticle size, zeta potential, count, asymmetry and fluorescence

Carr R., Hole P., Malloy A., Smith J., Weld A., Warren J., NanoSight Ltd, UK

A new nanoparticle sizing and characterisation technique is described which allows nanoparticles in a suspension to be individually but simultaneously detected and analysed in real time using a low cost instrument. Nanoparticles of all types [...]

Advanced fluorescent nanotracers: a broad field of application

Raccurt O., Samuel J., Poncelet O., Szenknect S., Tardif F., Laboratory of Tracers Technologies, FR

Optical and magnetic nanoparticles are both attractive fields of investigation which are gaining in importance due to their potential markets e.g. polymer nano-composite, colloidal dispersion, environmental monitoring or biomedical diagnostics, etc. Among all the spectroscopic [...]

Rhodamine B Isothiocyanate-Modified Ag Nanoaggregates on Dielectric Beads: A Novel Surface-Enhanced-Raman-Scattering and Fluorescent Imaging Material

Kim K., Lee H.B., Lee J.W., Jang H.J., Lee H.B., Lee J.W., Seoul National University, KR

Ag-deposited silica and polystyrene beads are efficient surface-enhanced-Raman-scattering (SERS) substrates that can be used as core materials of SERS-based biosensors. In this work, we report that once rhodamine B isothiocyanate (RhBITC) is adsorbed onto them, [...]

Dispersion and incorporation of optical nanotracers

Samuel J., Raccurt O., Poncelet O., Tillement O., Tardif F., Commissariat à l’Energie Atomique, FR

Silica fluorescent nanoparticles of 40nm diameter are synthesized by a reverse microemulsion process. Numerous industrial applications involve the homogeneous incorporation of nanoparticles into a polymer matrix. Nevertheless, because of their low size, nanoparticles tend to [...]

Single dot luminescence characteristics of CdSe/ZnS core-shell structured quantum dots with different ligands

Yu H., Song N.W., Moon D.W., Shin S.K., Korea Research Institute of Standards and Science, KR

Chemical derivatizations with different ligands were perfomed on CdSe/ZnS core-shell quantum dots (QDs). The role of ligands serves to increase water solubility and bio-compatibility of QDs for in-vivo biomedical fluorescence imaging. These QDs were synthesized [...]

Fluorescence of Water-Soluble Fullerenes in Biological Systems

Lin S., Jones D.X., Mount A.S., Ke P.C., Clemson University, US

The chemical and photophysical properties of fullerenes have been studied over the past two decades yet the biological applications of these nanoparticles remain limited. The major hurdle of integrating fullerenes with biological systems is their [...]

Chemical imaging using molecular spectroscopy – providing answers to fundamental biomedical questions at the nanoscale

Whitley A., Gilmore A., Tay L., Lee E., Adar F., HORIBA Jobin Yvon, US

HORIBA Jobin Yvon have been at the cutting edge of major breakthroughs in many key areas of instrument development and materials analysis including the latest hybrid approach of combining two or more techniques in one [...]