DNA – Page 3 – TechConnect Briefs

Atomic Force/Scanning Probe Microscopy of Pharmaceutical and Biological Materials

Chernoff D.A., Advanced Surface Microscopy, Inc., US

AFM is a valuable tool for a wide range of materials and device analysis. AFM images of particles and biopolymers are valued because direct visualization and measurement of individual objects complements the average measures obtained [...]

Evaluation of Nanoencapsulated DNA Vaccine for RSV

Boyoglu S., Vig K., Rangari V., Pillai S., Dennis V., Singh S.R., Alabama State University, US

Polymer nanoparticles have been used as carriers to enhance drug delivery. Among them chitosan is the most commonly used carrier, because it promotes long term of incorporated drugs. In the present study,we used DNA vaccine [...]

DNA-Associated Single-walled Carbon Nanotubes as a Platform for Drug Delivery

Dolash B.D., Lahiji R.R., Zemlyanov D.Y., Reifenberger R., Bergstrom D.E., Purdue University, US

DNA-associated single walled carbon nanotubes(DNA:SWCNTs) have shown potential in drug delivery with the ability to translocate across the cell membrane carrying various biomolecules. Our laboratory has completed a series of experiments to show the sonication [...]

Role of Nano-chirality and broken symmetry in hostile organism penetration of host cell DNA

Vezzoli G.C., Institute for the Basic Sciences, US

We show that broken symmetry, at the nano level, of biomolecules is key to phage invasion of a host cell, and take-over of the cell’s RNA-DNA replication processes. We determined that perturbation of cellular water [...]

DNA-guided Assembly of Organized Nano-Architectures

Gang O., Maye M.M., Nykypanchuk D., Xiong H., van der Lelie D., Brookhaven National Laboratory, US

Incorporation of DNA into nano-object design provides a unique opportunity to establish highly selective and reversible interactions between the components of nanosystems. Assembly approaches based on the nano-object’s addressability promise powerful routes for creation of [...]

Nanostructured Biomolecular Assemblies Based on DNA-Protein Interactions

Sroga G.E., Dordick J.S., Rensselaer Polytechnic Institute, US

Directed, biologically-driven self-assembly has the potential to yield hybrid multicomponent architectures with applications ranging from nanoelectronic devices to smart drug delivery systems and responsive materials. To enable these applications, it is critical to gain control [...]

Conducting Polymer Nanocomposites: Role of DNA Functionalized Carbon

Cheung W., Bogozi A., Ma Y., Mao G., Mao G., He H., Rutgers University, US

In this work, a water-soluble self-doped polyaniline nanocomposite was fabricated by in-situ polymerization of 3-aminophenylboronic acid monomers in the presence of single-stranded DNA dispersed- and functionalized- single-walled carbon nanotubes. For the first time, we found [...]

Solubilization of Single Wall Carbon Nanotubes with Salmon Sperm DNA

Kim S.N., Singh K., Ounchen F., Grote J., Naik R., NRC, US

In this paper, we present a solubilization study of commercially available SWCNTs by using the DNA extracted from waste materials of the salmon fishing industry through an enzyme isolation process. The optical properties, including UV-NIR [...]

Carbon Nanotube Interfaces for Single Molecular Level Bio Sensing

Choi W.B., Vedala H., Roy S., Kim T-H., Florida International University, US

Single molecule detection, aimed both at fundamental investigation and applications, has recently been attracting a lot of attentions. The present set of studies is focused on the design, fabrication and optimization of novel carbon nanotube(CNT) [...]

The Influence of DNA Wrapping on SWNT Optical Absorption in Perpendicular Polarization

Snyder S.E., Rotkin S.V., Lehigh University, US

Single-walled carbon nanotubes (SWNTs) hold great promise for the next generation of electronic devices due to their small, biologically compatible size, exceptional electronic properties, and the range of bandgaps accessible with variations in diameter and [...]