RU – Page 8 – TechConnect Briefs

Refined coarse-grain modeling of stamp deformation in nanoimprint lithography

Merino S., Retolaza A., Juarros A., Schift H., Sirotkin V., Svintsov A., Zaitsev S., IMT RAS, RU

The inhomogeneous distribution of the residual layer thickness is a vital issue in nanoimprint lithography (NIL). Using the simulation of NIL, this problem can be alleviated by optimizing the stamp geometry and by choosing process [...]

Reliability of Nano Devices and Systems: Nuclear Spins of Stable Magnetic Isotopes as the Reliability Factor of Biomolecular Nanoreactors

Koltover V.K., Institute of Problems of Chemical Physics, Russian Academy of Sciences, RU

The trend of “nanoscaling” brings engineering down to the dimensions of molecular structures. However, it also poses the problem of how to create a reliable system from molecular components experiencing permanent fluctuations? Fortunately, engineers may [...]

Laser diffraction study of inverse opals

Sinitskii A., Abramova V., Laptinskaya T., Tretyakov Yu., Moscow State University, RU

We discuss the experimental data on laser diffraction in tungsten oxide photonic crystal films with an inverse opal structure. The samples were prepared using deposition of monodisperse polystyrene microspheres onto a vertical glass substrate, infiltration [...]

Diffusion of Nanoparticles through the Tissues in Experiment

Reshetov I.V., Frank G.A., Sukharev S.S., Efremov G.D., Danileico Yu.C., Timoshenko V.Yu., P.A.Hertzen Moscow Research Oncological Institute (MROI), RU

We have created nanocrystals of silicon with sizes in the greatest measurement in the average 50 nm (from 4 to 100 nm), and nanocrystals of the oxide of aluminum with the adsorbed molecules of phthalocyanines, [...]

Mechanism of Action and Surfactant Influence During Chemotherapy of Brain Tumour Using Doxorubicin-Loaded Poly(Butyl Cyanoacrylate) Nanoparticles

Petri B., Bootz A., Khalanski A., Hekmatara T., Müller R., Kreuter J., Gelperina S., Moscow Medical Academy, RU

Polysorbate 80(Tween® 80)-coated poly(butyl cyanoacrylate) nanoparticles have been shown to enable the transport of doxorubicin (DOX) across the blood-brain barrier (BBB). This formulation produced a high antitumoral effect in an orthotopic model of the very [...]

Multicomponent Coatings Improve the Biocompatibility of Load-bearing Implants

Chissov V.I., Reshetov I.V., Frank G.A., Levashov E.A., Shtansky D.V., Filushin M.M., Efremov G.D., Sukharev S.S., P.A.Hertzen Moscow Research Oncological Institute, RU

New implants are studied in vivo under the conditions, when the replaced defect is located on the bone, which accomplishes motions with the large amplitude and with the large load.Three types of implants were placed [...]

Laser Heating of Sulphuretted Carbon Nanoparticles Inhibits Tumor Growth

Kogan B.Ya., Yakubovskaya R.I., Pankratov A.A., Andreeva T.N., Kvacheva L.D., Titov A.A., Puchnova V.A., Feysulova R.A., Vorozhtsov G.N., Organic Intermediates & Dyes Institute, RU

Light-absorbing nanoparticles incorporated in a tissue can be heated by short-pulsed laser irradiation up to several thousand Kelvin degrees. Average tissue temperature may be kept normal if the concentration of these particles is low. Antitumor [...]

The Nucleolus and Cellular Stress: Analysis by Coherent Phase Microscopy

Tychinsky V.P., Kretyshev A.V., Klemyashov I.V., Reshetov I.V., Vyshenskaya T.V., Shtil A.A., P.A.Hertsen Moscow Research Oncological Institute, RU

Coherent phase microscopy is a nanoscale measurement technique, an original method of monitoring the responses to cellular stress. We demonstrate that: 1) optically dense subcellular structures, including the nuclei and nucleoli, can be clearly detected [...]

Investigation of the Electronic Properties of the ZrO2 and HfO2 Thin Films by Scanning Probe Microscopy and X-ray Photoelectron Spectroscopy

Antonov D.A., Filatov D.O., Maximov G.A., Zenkevich A.V., Lebedinskii Yu.Yu., Nizhni Novgorod State University, RU

The advantages of the combined AFM/STM technique for investigating the dielectric properties of ultrathin MeOx layers with high spatial resolution is shown. Particularly, MO2/Si (M=Hf, Zr) interface evolution upon heat treatments is explored. It is [...]

Polydispersed Detonation Nanodiamond and Approaches for its Fractioning

Petrov I., Detkov P., Walch J., Shenderova O., Scientific and Industrial Company “New Technologies”, RU

We will discuss the rationale and methods of fractioning of the DND depending on the sizes of the agglomerates in the initial as-received DND powder. It is well known that primary (monocrystalline) DND particles have [...]