Nanocrystals of the fluorogenic precursor fluorescein diacetate (FDA) were applied as labels to enhance assay sensitivity in our previous studies. Each FDA nanocrystal can be converted into ~2.6 x 106 fluorescein molecules, which is useful [...]
We have measured the change of decay rate of 7Be in different environments including in atomic clusters such as fullerene C60. It has been found that the decay rate depends on the geometrical position of [...]
Fluorescent labeling reagents are used as diagnosis and research reagents that label specific protein, antigen, antibody, and DNA. However, the chromophoric groups are not stable under long-time Ultra Violet (UV) excitation measurement condition. Nanometer-sized semiconductor [...]
Nanotechnology involves working at the atomic, molecular, and macromolecular levels including imaging. Recently, four areas have emerged in cardiovascular imaging:1.Targeted therapeutics: delivering drugs where they are needed; 2.Tissue engineering to replace defective valves, damaged heart [...]
Recently there has been interest in the use of gold nanoparticles as a colorimetric method to detect the hybridization event of DNA [1-4]. The method uses the physical phenomena that nanoparticles of gold exhibits the [...]
The possibility of using nanodiamond as bioactive nano-probes for bio-object labeling and treatment is demonstrated. The conjugation of Nanodiamond crystals and bio-molecules are comparatively new but promising subject of interest for bio-applications, due to their [...]
Due to the increasing number of AMI patients accompanied with a difficulty in diagnosing the anomaly, a major push to develop innovative approaches to tackle the recognition of myocardial infarctions has been noticed. Most of [...]
We have developed a nanoparticle formation process based on rapid micromixing to produce high supersaturations, which we term Flash NanoPreciptiation.4, 5 This work introduces a novel approach that expands the applications of the Flash NanoPrecipitation [...]
The interactions of semiconductor quantum dots (QDs) with living cells remain poorly understood. It is known that certain sizes (colors) of QDs penetrate more readily into subcellular compartments, such as the nucleus, or into bacteria. [...]
Design and applications of “smart” multivalent fluorescent probes based on semiconductor nanocrystals and anticancer drug molecules will be presented. Various polymer coating strategies have been employed to insure stability and define composition of nanoparticles. Next, [...]
In this work we assess the use of atomic force microscopy (AFM) study combined with activity assays, DLS and fluorescent measurements for complex characterization of nanoparticle-protein conjugates. Image processing techniques were used to locate and [...]
, Bielinska A.U.
, Kariapper M.S.T.
, Khan M.K.
, Lesniak W.
, Nair B.M.
, Sinani V.A.
, Sun K.
, Waite E.
, Roswell Park Cancer Institute, US
Nanocomposites combine the properties of nano-sized inorganic guest atoms/molecules with their nanoscopic size polymer host. We have synthesized water-soluble, biocompatible, fluorescent, and stable nanocomposites with regulated surface charge and controlled size for cell labeling studies. [...]
Journal: TechConnect Briefs
Volume: 2, Technical Proceedings of the 2006 NSTI Nanotechnology Conference and Trade Show, Volume 2
Published: May 7, 2006
Industry sectors: Advanced Materials & Manufacturing | Medical & Biotech
Topics: Diagnostics & Bioimaging