Papers – Page 68 – TechConnect Briefs

Smart Bandage – A Hydrogel Supported Optical Microcavity Sensor

DeLouise L.A., University of Rochester, US

Developing new medical diagnostic technologies that can be used in the home for early detection and disease prevention is a central focus at the University of Rochester Center for Future Health. This paper is concerned [...]

Peptide Based Nanoparticles as a Platform for Vaccine Design

Raman S.K., Kao D.J., Tropel D., Graff A., Machaidze G., Hodges R.S., Burkhard P., Biozentrum, CH

To-date vaccines for many of the dreadful diseases such as Tuberculosis, Malaria, AIDS and Hepatitis are still ineffective or unavailable. Peptide based vaccines have been developed but because of their poor immunogenic response and the [...]

Electronic Sensing of Antibodies using Carbon Nanotube Devices

Teker K., Sivakumar K., Wickstrom E., Panchapakesan B., University of Delaware, US

Carbon nanotubes (CNTs) are remarkable solid state nanomaterials due to their unique properties such as high surface area, hollow cavities, and excellent mechanical and electrical properties. Interfacing carbon nanotubes with biological materials could enable significant [...]

Optimal Design of Laser Surgery for Cancer Treatment Through Nanoshell-Mediated Hyperthermia Therapy

Feng Y., Rylander N., Bass J., Oden J.T., Diller K., The University of Texas at Austin, US

Recent development of nanoparticle technology and its application in hyperthermia therapies makes it possible to consider optimal control of the temperature field and thermal energy delivered to the tumor region with minimal destruction of surrounding [...]

Photo-Enhanced Luminescence in Bio-conjugated Quantum Dots for Ovarian Cancer Biomarkers

Dybiec M., Korsunska N.E., Zhukov P., Zhukov T., Ostapenko S., Sellers T., Zajac A., Zhukov P., Zhukov T., University of South Florida, US

Ovarian cancer is the most lethal gynecologic malignancy. This largely reflects the fact that approximately 75% of cases are detected at advanced stages of disease, when cure is unlikely. In contrast, 5-year survival for patients [...]

The Evolution of Vievs of in vivo Use of Nanoparticles for Tumor Treatment

Chissov V.I., Reshetov I.V., Luskinovich P.N., Shepelev A.A, Efremov G.D., Matorin O.V., Sukharev S.S., P.A.Hertsen Moscow Research Oncological Institute (MROI), RU

The methods of site-specific delivery of antitumor agents without the general and system consecuences remain to be actual because the need to reduce the negative effects of antitumor treatment. In the experiment attempts are made [...]

Reconstruction of Load-Bearing Defects in Oncology by Using Nanomodification of Implants

Chissov V.I., Reshetov I.V., Levashov E.A., Shtansky D.V., Filushin M.M., Sukharev S.S., Bashkova I.A., Moscow Research Oncological Institute, RU

By means of nanotechnological approach different coating procedures enlarging biocompatibility factors of implants were developed. The well-known materials – titanium plates are used as substrates supporting structures. Depending on the construction type (stable or rolling) [...]

Effect of High AC Magnetic Field on Magnetic Nanoparticles for Magnetic Hyperthermia and Radiation/Chemotherapy Applications

Belc D., Chen C., Roberts R., Bettge M., Arora R., Mohite V., Florida State University, US

There are numerous studies in the field that explain and model the behavior and heating properties of magnetic nanoparticles (NPs) when exposed to an alternating magnetic field [1, 2]. Particularly for applications such as magnetic [...]

(Salen)Mn(III) Compound as a Nonpeptidyl Mimic of Catalase: Theoretical Study of the Reaction Mechanism and Comparison with (Salen)Mn Catalyzed Epoxidation Activities

Abashkin Y.G., Burt S.K., National Cancer Institute, US

Catalase mimics can be used as therapeutic agents against oxidative stress in treatment of many diseases including Alzheimer’s disease, stroke, heart disease, aging and cancer. (Salen)Mn(III) compounds have been proven to be promising as synthetic [...]

Chemotaxis of Metastatic Breast Cancer Cells in Parallel Gradient Microfluidic Chambers

Saadi W., Wang S-J, Lin F., Jeon N.L., University of California Irvine, US

Chemotaxis plays a key role in cancer metastasis, directing the motility of metastatic cells through gradients of growth factors or other chemoattractants. In order to rigorously characterize the role of growth factors in cancer cell [...]