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HomeTopicsBiomaterials

Topic: Biomaterials

Targeting Nanoparticles to Tumors using Adenoviral Vectors

Saini V., Enervold M.R., Perez A., Koploy A., Perkins G., Ellisman M.H., Green H.N., Mirov S.B., Zharov V.P., Everts M., University of Alabama at Birmingham, US
Despite advances in detection and treatment of cancer, development of novel therapies remains essential; in this regard, nanotechnology holds great promise. For example, tumor imaging opportunities have expanded by the development of quantum dots (QDs) [...]

Mathematical model of drug delivery using Anti-cancerous Herbal drugs

Katiyar V.K., Pathak P., Indian Institute of Technology, Roorkee, IN
Pharmacokinetics deals with the distribution of drugs, chemicals, tracers or radioactive substance among the various compartments of the human body. Compartment modeling is very convenient for biochemical transformation. In this paper, we have used basic [...]

Formation of Nano CoFe2O4 Crystallites in Hydroxyapatite

Pon-On W., Tang I.M., Mahidol University, TH
Embedding nano size CoFe2O4 ferrite particles in a hydroxyapatite (HAP) host would make them to better candidates for hyperthermia treatment of cancer. The formation of nano crystallites of CoFe2O4 ferrites in the hydroxyapatite Ca10-3xFe2xCox(PO4)6(OH)2 (where [...]

Gatifloxacin Nanoparticles For Ophthalmic Delivery

Motwani S.K., Ahmad F.J., Iqbal Z., Talegaonkar S., Khar R.K., Faculty of Pharmacy, Hamdard University, IN
Biodegradable colloidal nanoparticles of Poly (lactide-co-glycolide) (PLGA) have received considerable attention as a possible means of delivering drugs because of their biocompatibility and resorbability through natural pathways. As the ocular efficacy of drugs is greatly [...]

Gold nanoshells aided optical imaging in vitro, in vivo and ex vivo

Lee M., Loo C., Gobin A.M., West J., Halas N., Drezek R., Korea Electronics Technology Institute, KR
Scattering-based optical imaging technologies such as Optical Coherence Tomography (OCT) and Reflectance Confocal Microscopy (RCM) offer a unique non-invasive approach to the detection, diagnosis, and monitoring of cancer. In this article, we describe the use [...]

Heating efficiency of debundled carbon nanotubes compared to carbon black

Levi N.H., Carroll D.L., Wake Forest University, US
This work examines the amount of heat generated by single-wall and multi-wall carbon nanotubes to show how bundling and adequate dispersion of the tubes effects heat generation. Due to their high aspect ratio, nanotubes behave [...]

Synthesis, Properties and Biomedical Applications of Novel Core-Shell Iron Magnetic Nanoparticles

Qiang Y., Antony J., Sharma A., Meyer D., Faheem M., Campanell M., University of Idaho, US
Nanoparticles have gained increased attention recently for biomedical and environmental applications. Biocompatible magnetic nanoparticles (MNPs) have been found promising in several biomedical applications for tagging, imaging, drug delivery, sensing and separation in recent years. Most [...]

Differential lethality of gold nanoparticles is associated with immunogenecity

Huang G.S., Chen Y-S, Yeh H-W, National Chiao Tung University, TW
To obtain antibodies specifically recognizing gold nanoparticles (GNPs) BALB/C mice were immunized by weekly intra-peritoneal injection of adjuvant-emulsified 5 nm, 8 nm, 12 nm, 17 nm, and 37 nm GNPs. Mice injected with 8 nm, [...]

Design of Magnetic Nanoparticles for Purification of His-tagged Recombinant Proteins

Mohapatra S., Pal D., Ghosh S.K., Pramanik P., Indian Institute of Technology, IN
Manipulation of proteins effectively for in-vitro study is an important step of research in the area of proteomics. The expression of recombinant proteins with histidine fusion tags(6xHis) is widely used to ease their purification from [...]

Creation of an Aptamer Nanobiosensor for Ultra-Sensitive Detection of Heart Failure

Darnaud M., Ricketts A., Graham D., University of Strathclyde, UK
This project focuses on discovering a new aptamer sequence that binds specifically and with high affinity to Brain Natriuretic Peptide (BNP), which is indicative of the early stages of heart failure. A library of random [...]

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