This presentation describes the creation of protein nanoarrays on a nitrocellulose surface using Dip-Pen Nanolithography and their use in studying protein:protein interactions in an assay format.
Alexander J., Faulds K., Geboers M., Graham D., Senior L., Stevenson R., University of Strathclyde, UK
We report the first use of ‘bare’ nanoparticles as both a cellular delivery vehicle and a spectroscopic detection platform to enable surface enhanced resonance Raman scattering (SERRS) detection. We have shown how this approach can [...]
We have developed a novel surface enhanced resonance Raman scattering (SERRS) detection method that is amenable for almost any biological target. By utilising the information rich spectrum obtained from SERRS we show that we can [...]
Dougan J.A., Faulds K., Graham D., Haaheim J., Levesque T., Stevenson R., Stokes R.J., University of Strathclyde, UK
We have used Dip-Pen Nanolithography (DPN) to create biosensor arrays on micro- and nano-structured surfaces. Bespoke linker and labelling materials enables detection of biological molecules by surface enhanced resonance Raman scattering (SERRS). Careful DPN-directed placement [...]
Modification of oligonucleotides with gold nanoparticles was first reported ten years ago and opened up several new avenues of research as they can be used as a novel nanostructured building material but the conjugate can [...]