Topic: Biomaterials
Delivery of Shiga Toxin 1 A Subunit into Epithelial Cells Using Silica-Based Nanowires
Kwon N.H., Beaux M., Sheng H., Ebert C., Wang L., McIlroy D.N., Hovde C.J., Bohach G.A., University of Idaho, US
Silica-based nanowires were used to introduce the Shiga toxin 1 A subunit (StxA1) into bovine and human epithelial cells. We extended our previous technology which employs fibronectin (Fn) as a ligand to induce integrin-mediated uptake [...]
Differential Uptake of PEG-Silica-FITC Nanoparticles by Human Breast Cancer Cells and Normal Human Breast Epithelial Cells
Iwakuma N., Sharma P., Delano M.J., Moldawer L.L., Moudgil B.M., Grobmyer S.R., University of Florida, US
Background: An understanding of uptake of nanoparticles (NPs) by human cancer cells and non-cancer cells is important for the development of NPs as novel cancer therapeutic and diagnostic agents. Hypothesis: Uptake of NPs is increased [...]
An Investigation of Cellular Toxicity of Carbon Nanomaterials in African American Breast Cancer Cells
Functionalized CNTs and CNFs are attractive not only because they are theoretically easier to disperse in organic solvents and water, but also because there is some evidence that these modifications may enhance solubility and/or decrease [...]
Nanoprobe for Optical Molecular Imaging
Optical molecular imaging (OMI) is a very powerful tool for studying the temporal and spatial dynamics of specific biomolecules and their interactions in real time in vivo. It exhibits the great advantages of high temporal [...]
Chemical imaging using molecular spectroscopy – providing answers to fundamental biomedical questions at the nanoscale
HORIBA Jobin Yvon have been at the cutting edge of major breakthroughs in many key areas of instrument development and materials analysis including the latest hybrid approach of combining two or more techniques in one [...]
Optimisation of magnetoliposomes for biomedical multi-tasking; potential dual contrast agents and drug delivery vehicles
The relaxivity and particle size of both solid and aqueous-type magnetoliposomes are compared. The effect of magnetic filtration on the particle size and the size distribution is also examined. Our results suggest that magnetic filtration [...]
Characterization of Nano- & Microparticles Suitable for Drug & Gene Delivery by Freeze-fracture Electron Microscopy
The potency of drug/gene-loaded nanoparticles is frequently depending upon their morphology adopted in a biological relevant environment. Freeze-fracture electron microscopy (ff-em) is a powerful techniques to monitor the self-assembling of lipid-, polymer-, as well as [...]
Shape-controlled synthesis and functionalization of gold nanoparticles for hyperthermia applications
Control of nanoparticle shape may initially seem like a scientific curiosity, but its goal goes far beyond aesthetic appeal. The shape not only influences the chemical and optical properties of metal nanoparticles, but also their [...]
Nano gold can drop PSA level
abstract Reaches first finding nano gold under 10 nm can improve micturition. We did several tests for one who has prostate cancer. We find one who has PSA level 193 with harmony treatment for several [...]