Medical & Biotech – Page 121 – TechConnect Briefs

Mechanical Properties of Nano-Structure Controlled Ti-Hf Alloy for Dental Implant

Jeong Y.H., Choe H.C., Ko Y.M., Park S-J, Kim D.K., Brantley W., Chosun University, KR

Objectives: Cp-Ti has a excellent biocompatibility. So, it was widely used dental implants and artificial joint. But it is not strong enough for some dental applications. Since Hf belongs to the same group as Ti [...]

Nanocomposites for Restorative Dentistry

Uveges A., Bukovinszki K., Szaloki M., Hegedus C., Borbely J., University of Debrecen, HU

Dental filling materials are crosslinked resins with high abrasion resistance. Inorganic micro and recently nanofillers are introduced to improve their properties. However, the shrinkage of the resin component during the polymerization reaction is still a [...]

Nanodiamonds for Detoxification

Gibson N., Fitzgerald Z., Luo T.-J., Shenderova O., Grichko V., Bondar V., Puzur A., Brenner D., North Carolina State University, US

Our research deals with using nanodiamond particles as an enterosorbent to remove mycotoxins from the gastrointestinal tract. We are working on developing an ideal enterosorbent by obtaining appropriate size nanoparticles, modify nanodiamond surface groups, and [...]

Biocompatibilities of some synthetic polymers in films

Kim G., Kim H., Yoon J., Ree M., Kim G., Kim H., Pohang University of Science and Technology, KR

Materials for artificial devices require biocompatibility with the human body. Moreover, it has been well known that the implants are facilely tainted with pathogenic bacteria during surgical processes and that a few bacteria circulate in [...]

Protein binding to particle surfaces determines intracellular interaction and uptake kinetics

Ehrenberg M., McGrath J.L., University of Rochester, US

People are exposed to nanoparticles in from varying sources and in many ways. The goal of our research is to simplify this diverse problem by establishing a systematic understanding of the properties of particles that [...]

Phage-Derived Bioselective Nanovehicles for Drug and Gene Delivery

Petrenko V.A., Auburn University, US

Phage display technology rests on two fundamental concepts: combinatorial chemistry and fusion phage. We first demonstrated fusion of the major coat protein of the phage with foreign random peptides, which results in landscape phage libraries. [...]

Electrophoretic RNA Transport Through Transmembrane Carbon Nanotubes

Zimmerli U., Koumoutsakos P., ETH Zürich, CH

We study electrophoretic transport of RNA through carbon nanotubes embedded in membranes using molecular dynamics simulations. % Doped and naked carbon nanotubes are inserted into a dodecane membrane and a dimyristoylphosphatidylcholine lipid bilayer and we [...]

Favored Osteoblast Interactions with Aerosol Printed 3D Nano-to-Macro Hierarchical Architectures: The Promise of Nanocomposites as Orthopedic Prostheses

Liu H., Webster T.J., Brown University, US

Ceramic/polymer nanocomposites simulate bone in terms of its nanostructure and associated properties, thus, offering a promising new opportunity for bone regeneration in a natural way. Previous in vitro studies demonstrated that well-dispersed nanophase titania in [...]

Protons’ binding within nanometer scaled compartments of natural ionic reservoirs: Bacillus subtilis spores

Kazakov S., Bonvouloir E., Gazaryan I., Pace University, US

Dormant spores of bacteria of Bacillus genus are intriguing micrometer-scaled objects for a physico-chemical study. The most paradoxical feature of dormant spores is that, being metabolically inactive and resistant to environmental insults, they actually monitor [...]

Novel surface architectures for biomimetic lipid membranes

Reimhult E., Merz C., Ye Q., Textor M., Swiss Federal Institute of Technology (ETH Zürich ), CH

Many important biological processes occur at, via or across one of the various lipid membranes present in the cell. These include transport governed by transmembrane proteins constituting more than 50% of all drug targets of [...]