Berthier J., Joly P., Rivera F., Caillat P.
CEA-LETI, FR
Keywords: active pixel sensor, Beer-Lambert, chemiluminescence, diffusion, Michaelis Menten
Detection of hybridized targets—like DNA strands—in microsystems for biotechnology is usually done by fluorescence. However, recent investigations have shown that chemiluminescence could be a more effective and sensitive tool for detection under the condition that dispersion of light due to diffusion is not too important. In this study, a model for an enhanced chemiluminescence reaction using luminols is proposed and the resulting light emission and absorption by a CMOS APS (active pixel sensor) is calculated.
Journal: TechConnect Briefs
Volume: 2, Nanotechnology 2011: Electronics, Devices, Fabrication, MEMS, Fluidics and Computational
Published: June 13, 2011
Pages: 698 - 701
Industry sector: Advanced Materials & Manufacturing
Topic: Informatics, Modeling & Simulation
ISBN: 978-1-4398-7139-3