chemiluminescence – TechConnect Briefs

Analytical system capable of rapidly quantifying food-borne pathogen for food safety and public health

Khang J., Kim D., Chung K.W., Lee J-H., Luminescent MD, LLC, US

Cost-effective and easy-to-use biosensor was developed for the rapid quantification and monitoring of Escherichia (E.) Coli O157:H7 in sample using E. Coli O157:H7 aptamer, graphene oxide (GO)/iron nanocomposites, and guanine chemiluminescence detection. E. Coli O157:H7 [...]

Hybrid biosensor for the early diagnosis of breast cancer

Cho K., Chong S., Chong S., Park E., Lee J-H., Luminescent MD, LLC, US

A cost-effective and novel hybrid biosensor using the combination of antibody and DNA aptamer was developed for the early diagnosis of breast cancer. 1,1’-oxalyldiimidazle chemiluminescence (ODI-CL) was applied as a detector of the hybrid biosensor. [...]

Different contribution of carbon nanotubes and graphene oxide in single nucleotide polymorphism for the diagnosis of human mad-cow disease

Choi W., Lee J-H., Luminescent MD, LLC, US

Rapid single nucleotide polymorphism (SNP) with 1,1’-oxalylimidazole chemiluminescence (ODI-CL) detection was developed for the early diagnosis of human mad-cow disease. Mutated single strand DNA (ssDNA) sequence discovered from patients having human mad-cow disease rapidly hybridize [...]

Background free biosensor using the combination of graphene oxide and Fe3O4 nanoparticles

Cho S., Park L., Chung R., Lee J-H., Luminescent MD, LLC, US

Cost-effective and rapid biosensor with background free chemiluminescence (CL) detection was developed using ssDNA aptamer-conjugated 6-FAM fluorescein (DAF), graphene oxide bound with magnetic nanoparticle (GMN), and 3,4,5-trimethoxyphenylglyoxal (TMPG). When thrombin was incubated in TE buffer [...]

Development of rapid aptasensor using graphene oxide and 1,1’-oxalyldiimidazole chemiluminescence detection

Kwun J., Yun S., Lee J-H., Luminescent MD, LLC, US

Highly selective and sensitive aptasensor capable of rapidly quantifying Vibrio parahaemolyticus in the presence of Vibio cholera and Vibrio vulnificus was developed using an specific DNA aptamer, graphene oxide and 1,1’-oxalyldiimidazole chemiluminescence (ODI CL) detection. [...]

A Model for Enhanced Chemiluminescence Reactions in Microsystems

Berthier J., Joly P., Rivera F., Caillat P., CEA-LETI, FR

Detection of hybridized targets—like DNA strands—in microsystems for biotechnology is usually done by fluorescence. However, recent investigations have shown that chemiluminescence could be a more effective and sensitive tool for detection under the condition that [...]

A novel on chip analysis of dissolved Hg(II) in drinking water

Deshpande K., Mishra R.K., Pal S., Danielsson B., Willander M., Bhand S., Birla Institute of Technology & Science, Pilani-Goa Campus, IN

A novel biochip based detection for determination of ultra trace mercury (Ii), lead(II) and cadmium (II)in drinking water. High through put analysis, low sample volume, high sensitivity and rapid analysis is the hallmark of the [...]

Fabrication of Microfluidic Cells with Liquid Core Waveguide and 1,1’-Oxalydiimidazole Chemiluminescence Detection

Lee J-H., Tartaglia A., Schlautman M.A., Carraway E.R., Clemson University, US

We have developed simple and inexpensive microfluidic cells (inner diameter: 100 _m) based on the principles of liquid core waveguide (LCW) and rapid 1, 1’-oxalyldiimidazole derivative chemiluminescence (ODI-CL) reactions. The microfluidic cells devised in this [...]