Development of Nanoconjugate with Different Monoclonal Antibodies to Inhibit Molecular Targets Important for Tumor Angiogenesis
Fujita M., Khazenzon N.M., Lee B-S, Holler E., Black K.L., Ljubimova J.Y., Cedars-Sinai Medical Center, US
Tumor cell-specific drug targeting is the major goal of nanotechnology-based platforms. A nanoconjugate Polycefin was synthesized for targeted delivery of antisense oligonucleotides and antibodies into tumors. The delivery of antisense oligonucleotides to α4 and β1 [...]