toxicity – Page 2 – TechConnect Briefs

Cytotoxicity of silver nanoparticles

Sotiriou G.A., Pratsinis A., Pratsinis S.E., Leroux J.-C., Pratsinis A., Pratsinis S.E., Particle Technology Laboratory, ETH Zürich, CH

Silver nanoparticles are receiving more and more attention for their plasmonic colors and their antibacterial effects [1]. The addition of a nanothin SiO2 shell minimizes the release of toxic Ag ions and the contact of [...]

Toxicity of Titanium Dioxide Nanoparticles on Growth Kinetics of Activated Biomass

Das P., Bagdiya N., Kumar A., IIT Delhi, IN

The objective of this study was to study the effect of titanium dioxide (TiO2) NPs on growth kinetic parameters of aerobic sludge bacteria. TiO2 NPs (2 mg/L and 20 mg/L concentrations) were exposed to activated [...]

Uptake and Elimination Behaviors of Polyethyleneimine (PEI)-Coated Multi-Walled Carbon Nanotubes by Eisenia Foetida and Daphnia Magna

Petersen E.J., Pinto R.A., Mai D.J., Landrum P.F., Zhang L., Huang Q., Shi X., Weber Jr W.J., National Institute of Standards and Technology, US

Hyphenated mass spectrometry (gas chromatography/mass spectrometry) techniques have been employed as one of the primary analytical tools for investigating the effects of ionizing radiation, chemical/biological carcinogens and oxygen derived free radicals on the induction and [...]

Polymalic acid-based nanodrugs: Anti-tumor efficacy and host compatibility

Holler E., Ding Hui, Patil R., Portilla J., Inoue S., Gangulum P., McNeil S.E., Patri A., Dobrovolskaia M.A., Black K.L., Ljubimova J.Y., Cedars-Sinai Medical Center, US

A polyanionic drug carriers is presented that penetrates biobarriers and targets molecular cancer markers of human breast and brain cancer. The carrier platform is poly(beta-L-malic acid) (PMLA), which is highly water soluble and biodegradable to [...]

A new model for toxicity of uranium dust

Zucchetti M., Massachusetts Institute of Technology, US

Depleted Uranium (DU) is mostly composed by the natural radioactive isotope U238 and it is a by-product of the enrichment process, that part of the nuclear reactors fuel cycle that produces the nuclear fuel to [...]

A new model for toxicity of uranium dust

Zucchetti M., Massachusetts Institute of Technology, US

Depleted Uranium (DU) is mostly composed by the natural radioactive isotope U238 and it is a by-product of the enrichment process, that part of the nuclear reactors fuel cycle that produces the nuclear fuel to [...]

Assessment of comparative toxicity of nano- and microparticles of magnetite

Katsnelson B.A., Privalova L.I., Degtyareva T.D., Kuzmin S.V., Sutunkova M.P., Minigalieva I.A., Kireyeva E.P., Khodos M.Y., Shur V.Y., Nikolaeva E.V., Valamina I.E., Tulakina L.G., Pichugova S.V., Beykin J.B., Federal State Institution of Sciences Medical Research, RU

Assessment of toxicity of 10 nm, 50 nm and 1 um Fe3O4 particles based on shift in the cell population of the broncho-alveolar lavage fluid after their intratracheal instillation into lungs of rats and on [...]

Effect of Carbon Nanotubes on Chinese Hamster Ovarian Cells

Chen H.H., Chen M., Luca J.A., Chen H.H., Chen M., Point Loma Nazarene University, US

We report the effect of carbon nanotubes at the cellular level using purified single-walled carbon nanotubes (SWNTs) resuspended in physiological compatible phosphate buffered saline (PBS) and systematically study its impact on Chinese Hamster Ovarian (CHO) [...]

Indium Phosphide : Cadmium Free Quantum Dots for Cancer Imaging and Therapy

Chibli H., Carlini L., Park S., Dimitrijevic N., Nadeau J.L., McGill University, CA

We synthesised Indium phosphide (InP) quantum dots (QDs) with different shell layer. We demonstrate highly fluorescent labeling of cell lines after nonspecific endocytosis of the QD. With spin-trap electron paramagnetic resonance (EPR) spectroscopy and reporter [...]

Express Control of Toxicity and Content of Patulin by Optical Biosensors

Starodub N.F., Pilipenko I.V., Pilipenko L.N., Pilipenko I.V., Pilipenko L.N., Katsev A.M., National University of Life and Environmental Sciences of Ukraine, UA

In this report the experimental data about the determination of P toxicity by optical biosensors based on the application of chemiluminescence (ChL) of Daphnia magna living media (ChL-test) and bioluminescence (BL) of Ukrainian strains of [...]